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Protéines et Peptides
Numéro de catalogue:
(PRSI92-146)
Fournisseur:
ProSci Inc.
Description:
Tumour Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumour cell lines and can be induced by TNF- alpha.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4815P)
Fournisseur:
ProSci Inc.
Description:
HINT1 peptide is used for blocking the activity of HINT1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-052)
Fournisseur:
ProSci Inc.
Description:
Human recombinant Bace13 (from HEK293 cells)
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI91-118)
Fournisseur:
ProSci Inc.
Description:
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. The FABP3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. FABP3 is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of onset of pain.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3807P)
Fournisseur:
ProSci Inc.
Description:
AIM peptide is used for blocking activity of AIM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4215P)
Fournisseur:
ProSci Inc.
Description:
ORAI3 peptide is used for blocking the activity of ORAI3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-522)
Fournisseur:
ProSci Inc.
Description:
Mouse Interleukin 36 beta (IL-36B)is a member of the IL-1 family of proteins. It is a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signalling pathways in target cells linked to a pro-inflammatory response. IL-36B is synthesised in several cells including resting and activated monocytes, and B cells. The receptor for IL-36 beta is thought to be a combination of IL-1 Rrp2 and IL-1 RAcP. Interleukin 36 beta is one part of the IL-36 signalling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Interleukin 36 beta are involved in a number of fundamental biological processes such as stimulating production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes, inducing expression of a number of antimicrobial peptides including beta-defensin 4 and beta-defensin 103 as well as a number of matrix metalloproteases , inducing the production of proinflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23, and activating p38 MAPK phosphorylation in BMDCs.Moreover, interleukin 36 beta may be involved in skin inflammatory response by acting on keratinocytes, dendritic cells, and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. It plays an important role in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II and inducing the production of IFN-gamma, IL-4 and IL-17 by T helper 1 (Th1) cells, cultured CD4+ T cells and splenocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5371P)
Fournisseur:
ProSci Inc.
Description:
JMJD1C peptide is used for blocking the activity of JMJD1C antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5863P)
Fournisseur:
ProSci Inc.
Description:
VENTX peptide is used for blocking the activity of VENTX antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5867P)
Fournisseur:
ProSci Inc.
Description:
WDR35 peptide is used for blocking the activity of WDR35 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3351P)
Fournisseur:
ProSci Inc.
Description:
Bax peptide is used for blocking the activity of Bax antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-488)
Fournisseur:
ProSci Inc.
Description:
Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3045P)
Fournisseur:
ProSci Inc.
Description:
p53DINP1 peptide is used for blocking the activity of p53DINP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3041P)
Fournisseur:
ProSci Inc.
Description:
PUMA peptide is used for blocking the activity of PUMA antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-410)
Fournisseur:
ProSci Inc.
Description:
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5303P)
Fournisseur:
ProSci Inc.
Description:
ABIN3 peptide is used for blocking the activity of ABIN3 antibody.
UOM:
1 * 50 µG
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