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Protéines et Peptides
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.
Numéro de catalogue:
(PRSI92-074)
Fournisseur:
ProSci Inc.
Description:
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
UOM:
1 * 50 µG
Fournisseur:
Shenandoah Biotechnology
Description:
Fibroblast growth factor 10 (FGF-10) is a growth factor that is important during embryonic development, especially during lung, limb, brain, heart, and kidney morphogenesis.FGF-10 is expressed in mesenchymal cells and facilitates epithelial-mesenchymal signaling through binding the epithelially expressed FGF receptor 2b (FGFR2b). FGF-10 also functions as a mitogen for keratinising epidermal cells, and induces the migration and invasion of cancer cells.
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.
Fournisseur:
Shenandoah Biotechnology
Description:
Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Fournisseur:
Shenandoah Biotechnology
Description:
Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).
Numéro de catalogue:
(J63250.MA)
Fournisseur:
Shenandoah Biotechnology
Description:
B cell-activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a type II member of the tumor necrosis factor (TNF) superfamily. BAFF is expressed as a transmembrane protein on T cells, macrophages, and dendritic cells. The transmembrane domain of BAFF can also be cleaved to produce a soluble protein fragment.
Fournisseur:
Shenandoah Biotechnology
Description:
Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
Numéro de catalogue:
(A0850.0050)
Fournisseur:
PanReac AppliChem
Description:
Bovine serum albumin (BSA)
UOM:
1 * 50 g
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Caspase-3 inhibitor III
Fournisseur:
Merck Millipore (Oncogene)
Description:
Streptavidin
Numéro de catalogue:
(431784-5)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
PHA-L is a potent lymphocyte mitogen with a narrow range. Requires calcium and manganese ions for activity. It has also been found to be useful as a specific marker in anterograde neuronal tracing.
UOM:
1 * 5 mg
Numéro de catalogue:
(420307-50)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Native kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.
UOM:
1 * 50 µG
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Human albumin (from serum)
Fournisseur:
Merck Millipore (Calbiochem)
Description:
Human albumin (from serum)
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