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Protéines et Peptides
Numéro de catalogue:
(PRSI5417P)
Fournisseur:
ProSci Inc.
Description:
IA-6 peptide is used for blocking the activity of IA-6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5479P)
Fournisseur:
ProSci Inc.
Description:
FAM59A peptide is used for blocking the activity of FAM59A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-477)
Fournisseur:
ProSci Inc.
Description:
Interleukin-6 receptor subunit beta (IL6ST) is also known as IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130 (gp130), CD130, Oncostatin-M receptor subunit alpha and Il6st,which is single-pass type I membrane protein. IL6ST /gp130 /CD130 can be found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver and found in all the cell lines tested except BaF-B03.The expression of IL-6ST /gp130 is not restricted to IL6-responsive cells. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. IL6ST /CD130 can bind to IL6 /IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduce the signal. IL6ST /GP130 does not bind IL6 and may have a role in embryonic development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5259P)
Fournisseur:
ProSci Inc.
Description:
SCARA5 peptide is used for blocking the activity of SCARA5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-550)
Fournisseur:
ProSci Inc.
Description:
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-227)
Fournisseur:
ProSci Inc.
Description:
OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5217P)
Fournisseur:
ProSci Inc.
Description:
PNAS4 peptide is used for blocking the activity of PNAS4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1158P)
Fournisseur:
ProSci Inc.
Description:
DR3 peptide is used for blocking the activity of DR3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1159P)
Fournisseur:
ProSci Inc.
Description:
FLIP peptide is used for blocking the activity of FLIP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3557P)
Fournisseur:
ProSci Inc.
Description:
CTRP1 peptide is used for blocking the activity of CTRP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7231P)
Fournisseur:
ProSci Inc.
Description:
13 amino acid peptide near the center of human IL-15.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3359P)
Fournisseur:
ProSci Inc.
Description:
NADE peptide is used for blocking the activity of NADE antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-698)
Fournisseur:
ProSci Inc.
Description:
Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I membrane protein. SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. SIRPG interacts with CD47. On binding with CD47, CD172g mediates cell-cell adhesion.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-727)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-734)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-741)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) is also known as Osteoclastogenesis inhibitory factor (OCIF), Osteoprotegerin (OPG). TNFRSF11B is a secreted homodimer protein, which can interact with TNFSF10 and TNFSF11. TNFRSF11B acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TNFRSF11B inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
UOM:
1 * 1 EA
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