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Protéines et Peptides
Numéro de catalogue:
(PRSI3257P)
Fournisseur:
ProSci Inc.
Description:
The peptide is used for blocking the activity of APOBEC3G antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3281P)
Fournisseur:
ProSci Inc.
Description:
TLR8 peptide is used for blocking the activity of the TLR8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3289P)
Fournisseur:
ProSci Inc.
Description:
MD-2 peptide is used for blocking the activity of MD-2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-392)
Fournisseur:
ProSci Inc.
Description:
Adiponectin is a secreted protein. It is Synthesised exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilisation and fatty-acid combustion. Adiponectin also antagonises TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signalling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodelling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6975P)
Fournisseur:
ProSci Inc.
Description:
SELK peptide is used for blocking the activity of SELK antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6945P)
Fournisseur:
ProSci Inc.
Description:
DDX60 peptide is used for blocking the activity of DDX60 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-052)
Fournisseur:
ProSci Inc.
Description:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3903P)
Fournisseur:
ProSci Inc.
Description:
SHP2 peptide is used for blocking activity of SHP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-137)
Fournisseur:
ProSci Inc.
Description:
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and quality control of newly synthesised glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumour cells, increasing phagocytosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-100)
Fournisseur:
ProSci Inc.
Description:
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-650)
Fournisseur:
ProSci Inc.
Description:
The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues. PRLRs are expressed in normal and neoplastic human breast tissue, and in most breast cancer cells. PRLR contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region required for the activation of the Jak2–Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes. PRLRs have also been observed in ovarian follicular cells of mice, pigs, sheep, deer, and humans, as well as in luteal tissue in cow and horse ovaries. Furthermore, PRLR knockout mice exhibit failure of embryonic implantation, reduced number of mature oocytes, and low fertilisation rates. Knockout females also display a reduced number of primary follicles.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-602)
Fournisseur:
ProSci Inc.
Description:
High temperature requirement protein A2(HTRA2) is a single-pass membrane protein .It contains 1 PDZ (DHR) domain and belongs to the peptidase S1C family. HtrA2 can be released from the mitochondria during apoptosis and uses its four most N-terminal amino acids to mimic a caspase and be recruited by IAP caspase inhibitors such as XIAP and CIAP1/2. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. The protein cleaves THAP5 and promotes its degradation during apoptosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-451)
Fournisseur:
ProSci Inc.
Description:
IL2RG contains one fibronectin type-III domain. IL2RG is an important signalling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4333P)
Fournisseur:
ProSci Inc.
Description:
Avian Influenza A M2 peptide is used for blocking the activity of M2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4335P)
Fournisseur:
ProSci Inc.
Description:
Strep-tag II peptide is used for blocking the activity of strep-tag II antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-996)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin-Conjugating Enzyme E2 J2 (UBE2J2) belongs to the ubiquitin-conjugating enzyme family. UBE2J2 is involved in the ubiquitiantion. UBE2J2 located in the membrane of the endoplasmic reticulum, catalyzes the covalent attachment of ubiquitin to other proteins. UBE2J2 may play a important role in the selective degradation of misfolded membrane protein from the endoplasmic reticulum.
UOM:
1 * 50 µG
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