Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI91-572)
Fournisseur:
ProSci Inc.
Description:
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-645)
Fournisseur:
ProSci Inc.
Description:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-732)
Fournisseur:
ProSci Inc.
Description:
Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
UOM:
1 * 1 EA
Fournisseur:
QIAGEN
Description:
Drug metabolism (DM), pharmacokinetic (PK) and toxicokinetic (TK) studies provide crucial insight into how drug candidates behave in the body and are therefore critical steps in drug development.
Fournisseur:
Shenandoah Biotechnology
Description:
Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.
Fournisseur:
Resonac
Description:
NI-424, I-524A
- Colonnes pour l'analyse des anions en utilisant la méthode sans suppresseur - NI-424 est compatible avec l'analyse simultanée des ions fluorure et phosphate
Numéro de catalogue:
(PRSI29-069)
Fournisseur:
ProSci Inc.
Description:
GRHL3 is a member of the grainyhead family of transcription factors. GRHL3 interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6823)
Fournisseur:
ProSci Inc.
Description:
WDR5 Antibody: WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5681)
Fournisseur:
ProSci Inc.
Description:
TMEM184A Antibody: TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(STMC100-1396)
Fournisseur:
STEMCELL Technologies
Description:
Stimulating T cells with the HPV18 (L1) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. A lyophilised mixture of 140 peptides from major capsid protein L1 of human papillomavirus type 18 (HPV18), HPV18 (L1) Peptide pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 568 on L1. L1 enters the nuclei of host cells and can assemble into virus-like particles (Stauffer <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:
1 * 1 UO
New Product
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Numéro de catalogue:
(PRSI79-502)
Fournisseur:
ProSci Inc.
Description:
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC gamma1.
UOM:
1 * 1 EA
Fournisseur:
Corning
Description:
Named for the site at which it was developed, the Roswell Park Memorial Institute, RPMI 1640 is a modification of McCoy's 5A containing an increased level of inositol.
Numéro de catalogue:
(PRSI56-309)
Fournisseur:
ProSci Inc.
Description:
ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-038)
Fournisseur:
ProSci Inc.
Description:
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.
UOM:
1 * 400 µl
New Product
Fournisseur:
Thermo Fisher Scientific
Description:
Use Thermo Scientific™ SureSTART™ 18 mm Precision Screw Caps with screw vials that have an 18 mm opening, including our SureSTART 10 mL and 20 mL Screw Top Headspace Vials (Level 3). Select Level 3 products for ultimate performance and sensitivity from your methods, while maintaining the highest levels of sample security and integrity.
Numéro de catalogue:
(AATB2001)
Fournisseur:
AAT BIOQUEST
Description:
DABCYL acid is one of the most popular acceptors for developing FRET-based nucleic acid probes suh as Molecular Beacon-based PCR probes.
UOM:
1 * 5 g
New Product
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