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Ace+Method+Development+Kits
Numéro de catalogue:
(BOSSBS-1531R-A750)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1531R-FITC)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB1141)
Fournisseur:
AAT BIOQUEST INC
Description:
AAT Bioquest's mFluor™ dyes are developed for multicolor flow cytometry-focused applications.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI25-635)
Fournisseur:
ProSci Inc.
Description:
BCAS2 belongs to the SPF27 family. It is involved in mRNA splicing. The protein might play an important role in breast cancer development by increasing the estrogen receptor's function.
UOM:
1 * 50 µG
Numéro de catalogue:
(AATB206)
Fournisseur:
AAT BIOQUEST INC
Description:
4'-(Aminomethyl)fluorescein is an excellent building block for developing fluoresceinated bioconjugates.
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(PRSI33-852)
Fournisseur:
ProSci Inc.
Description:
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. [RefSeq].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(AATB13479)
Fournisseur:
AAT BIOQUEST INC
Description:
The weakly fluorescent AMC substrates generate the bright blue fluorescent AMC product that has Ex/Em = 351/430 nm, and can be easily detected with a DAPI filter set.
UOM:
1 * 5 mg
New Product
Fournisseur:
AAT BIOQUEST INC
Description:
AAT Bioquest's iFluor® A7 dye was developed for labeling proteins, in particular, antibodies.
Numéro de catalogue:
(BOSSBS-6463R-A647)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6463R-A555)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6463R-HRP)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(TAAGTGG0003)
Fournisseur:
KREGLINGER EUROPE
Description:
Dehydrated enrichment media for growing Salmonella spp., Staphylococcus aureus, Escherichia coli and Listeria monocytogenes in food samples. It contains selected growth factors and nutritional requirements optimized to promote pathogens development.
UOM:
1 * 1 ST
Fournisseur:
AAT BIOQUEST INC
Description:
6-FAM alkyne is an excellent building block for developing fluoresceinated bioconjugates by reacting with an azide group.
Numéro de catalogue:
(AATB12632)
Fournisseur:
AAT BIOQUEST INC
Description:
IDA succinimidyl ester is an amino-reactive building block that can be used to develop a variety of IDA probes for detecting polyHis-containing proteins, and tools for purifying polyHis tagged proteins.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(AATB50016)
Fournisseur:
AAT BIOQUEST INC
Description:
Danofloxacin-HRP conjugate is used for developing an ELISA assay for quantifying danofloxacin.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI48-383)
Fournisseur:
ProSci Inc.
Description:
Also known as LRRN6A (leucine-rich repeat neuronal 6A), LINGO1 is a newly discovered gene that is expressed primarily in the central nervous system during early embro development, and may be an essential protein in the development of the nervous system.
UOM:
1 * 50 µG
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