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Masterflex+Single-use+Flow+Sensor
Numéro de catalogue:
(BOSSBS-12323R-FITC)
Fournisseur:
Bioss
Description:
Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11081R-FITC)
Fournisseur:
Bioss
Description:
The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including ∫-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.
UOM:
1 * 100 µl
Fournisseur:
Merck
Description:
Millipore's 37 mm Aerosol analysis monitors are transparent, disposable, plastic filter holders pre-assembled with Type MF (mixed cellulose esters) Millipore filters. A thin cellulose support seals the filter between monitor sections to distribute sample flow evenly over the filter surface. The three-part design holds the filter in-place when the top section is removed for open aerosol sampling.
Numéro de catalogue:
(BOSSBS-11951R-A555)
Fournisseur:
Bioss
Description:
The Per-Arnt-Sim (PAS) domain was identified as a 270 amino acid motif that mediates associations between various PAS family transcription factors. Several PAS domain family members have been identified including AhR, Arnt 1, and single-minded proteins (SIM1 and SIM2). The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, glutathione S-transferase Ya subunit and DT-diaphorase. The Ah receptor nuclear translocator protein 1 (Arnt 1) is required for ligand- dependent nuclear translocation of the Ah receptor and is also necessary for Ah receptor binding to the XRE element. Both SIM1 and SIM2 inhibit AhR/Arnt dimerization, thus inhibiting transcriptional activation. The SIM genes are thought to be involved in the directing and regionalization of tissues during development and the SIM2 gene, which is located on chromosome 21, is a candidate for the gene responsible for Down syndrome.
UOM:
1 * 100 µl
Numéro de catalogue:
(NOVUNB100-56527)
Fournisseur:
Novus Biologicals
Description:
The Caspase-8 Antibody (90A992) from Novus Biologicals is a mouse monoclonal antibody to Caspase-8. This antibody reacts with human, primate. The Caspase-8 Antibody (90A992) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry-Paraffin, CyTOF-ready.
UOM:
1 * 0,1 mg
Numéro de catalogue:
(TEST0618.0071)
Fournisseur:
TESTO
Description:
Flexible and high-precision for temperature measurements: The digital temperature probe with flexible probe shaft (together with the compatible measuring instrument) is ideal for carrying out measurements in locations that are difficult to access and in liquids.
UOM:
1 * 1 ST
New Product
Fournisseur:
Novus Biologicals
Description:
The Sulfatase-2 / SULF2 Antibody (2B4) from Novus Biologicals is a mouse monoclonal antibody to Sulfatase-2 / SULF2. This antibody reacts with human, mouse. The Sulfatase-2 / SULF2 Antibody (2B4) has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Paraffin, CyTOF-ready.
Fournisseur:
Novus Biologicals
Description:
The Calnexin Antibody from Novus Biologicals is a rabbit polyclonal antibody to Calnexin. This antibody reacts with human, mouse, rat, hamster. The Calnexin Antibody has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.
Numéro de catalogue:
(ROCK012-001-334)
Fournisseur:
Rockland Immunochemicals
Description:
Rat IgG2b Kappa isotype control can be utilized as a control or standard reagent in Western Blotting, Flow Cytometry, and ELISA experiments where determination of sample isotype is important. Specific conditions should be optimized by user.
UOM:
1 * 500 µG
Numéro de catalogue:
(BOSSBS-12122R-A647)
Fournisseur:
Bioss
Description:
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12361R-CY5)
Fournisseur:
Bioss
Description:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. FLRT1 (fibronectin leucine rich transmembrane protein 1) is a 646 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten LRR repeats. Expressed in kidney and brain, FLRT1 is thought to play a role in cell adhesion and receptor signaling. FLRT1 shares similarity with FLRT2 and FLRT3 and is subject to post-translational N-glycosylation. The gene encoding FLRT1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12333R-CY5)
Fournisseur:
Bioss
Description:
ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11955R-CY5)
Fournisseur:
Bioss
Description:
SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Fournisseur:
Novus Biologicals
Description:
The ABCA1 Antibody (HJ1) from Novus Biologicals is a mouse monoclonal antibody to ABCA1. This antibody reacts with human, mouse, rat, rabbit. The ABCA1 Antibody (HJ1) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.
Numéro de catalogue:
(ROCK610-102-043)
Fournisseur:
Rockland Immunochemicals
Description:
Anti-Mouse IgG3 secondary antibody is suitable for Flow Cytometry, immunochemistry and Immunofluorescence Microscopy, ELISA, western blotting as well as other anti IgG2b antibody based assays.
UOM:
1 * 1 mg
Numéro de catalogue:
(ROCK012-008-041)
Fournisseur:
Rockland Immunochemicals
Description:
Rat IgG2a isotype control can be utilized as a control or standard reagent in Western Blotting, Flow Cytometry, and ELISA experiments where determination of sample isotype is important. Specific conditions should be optimized by user.
UOM:
1 * 500 µG
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