Masterflex+Single-use+Flow+Sensor
Fournisseur:
KARTELL
Description:
These single channel pipettes are available with fixed volumes in a range from 5 to 1000 µl.
Numéro de catalogue:
(SPECSTUBEGN15391S)
Fournisseur:
Spectrum Laboratories
Description:
ProConnex® standard flow path for MiniKros sampler, 1 L.
UOM:
1 * 1 ST
Numéro de catalogue:
(MANA740654.100)
Fournisseur:
MACHEREY-NAGEL
Description:
Buffer, NTC, for clean up of single stranded DNA, 100 ml, Macherey-Nagel
UOM:
1 * 100 mL
Numéro de catalogue:
(189-0033)
Fournisseur:
KNF
Description:
Système de pompe à vide SC 920 G est à vitesse régulée.
Application: Évaporation rotative, distillation.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-2927R-A488)
Fournisseur:
Bioss
Description:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11623R-CY7)
Fournisseur:
Bioss
Description:
PIRT is a 137 amino acid multi-pass membrane protein. Highly conserved among vertebrates, PIRT consists of two transmembrane domains and one putative C-terminal phosphoinositide-binding domain. Although PIRT is expressed in peripheral nervous system, with highest levels in dorsal root ganglion and trigeminal neurons, and lowest levels in sympathetic and enteric neurons, it is not expressed in spinal cord. PIRT is a required component of the VR1 complex, which positively regulates VR1, a sensor of both noxious heat and capsaicin. Correspondingly, PIRT knockout results in impaired responses to noxious heat and capsaicin exposure, while VR1 remains unaltered. The gene that encodes PIRT maps to human chromosome 17p13.1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-A680)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyses, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-A750)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyses, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1091R-FITC)
Fournisseur:
Bioss
Description:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8526R-A350)
Fournisseur:
Bioss
Description:
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1091R-A555)
Fournisseur:
Bioss
Description:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
UOM:
1 * 100 µl
Numéro de catalogue:
(135-2904)
Fournisseur:
EUROCLONE
Description:
Aura Mini™ Cabinets are compact down-flow cabinets, provide an ultimate cleanliness Class 100 work area where the highest safety for the products is achieved. The internal design, the air flow aerodynamics, the special H14 filter and the Filtrete® exhaust filter (or prefilters) guarantees the highest performances at the most stringent safety levels and operator comfort.
UOM:
1 * 1 ST
Numéro de catalogue:
(GILSF161406)
Fournisseur:
GILSON
Description:
This convenient pipette holder has been designed to hold one single or multi channel pipette.
UOM:
1 * 1 ST
Numéro de catalogue:
(BURK5780-0040)
Fournisseur:
BURKLE
Description:
Pompe vide-fût électrique pour le refoulement de diesel, d'huile EL, d'anti-gel non dilué et d'autres liquides de la classe de risque AIII (VbF).
La protection anti-effet siphon intégrée empêche toute fuite en cas de tuyau défectueux. Disponible pour 230 V.
UOM:
1 * 1 ST
Fournisseur:
LEICA MICROSYSTEMS
Description:
Les caméras couleur Leica (fond clair) offrent une fidélité des couleurs exceptionnelle grâce à des algorithmes d'interpolation des couleurs de pointe réalisés dans la tête de la caméra. Les caméras Leica à fluorescence offrent une haute sensibilité du capteur - permettant des temps d'exposition courts et empêchant ainsi le photoblanchiment et protégeant activement les cellules de tout dommage photographique.
Numéro de catalogue:
(390-1597)
Fournisseur:
Binder
Description:
Door lock - lockable door handle (single door), KBF-S ECO
UOM:
1 * 1 ST
Appel de prix
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l' est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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