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Masterflex+Single-use+Flow+Sensor
Numéro de catalogue:
(736-0354)
Fournisseur:
Greiner Bio-One
Description:
AMPLIseal™ est un film de scellage auto-adhésif qui se distingue par sa faible autofluorescence, notamment dans la gamme de longueurs d'onde critique pour la PCR en temps réel. Il est constitué d'un film épais en PP recouvert d'un adhésif transparent en acrylate. La couche adhésive est protégée par un film décollable en polyester. L'adhésif en acrylate à forte adhérence offre un scellage fiable qui limite l'évaporation, sans pour autant perturber la réaction PCR ou les mesures de fluorescence.
UOM:
1 * 100 ST
Numéro de catalogue:
(PRSI92-673)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN- gamma by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI56-437)
Fournisseur:
ProSci Inc.
Description:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex, required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. A pseudogene exists on chromosome Yp11.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI28-486)
Fournisseur:
ProSci Inc.
Description:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-487)
Fournisseur:
ProSci Inc.
Description:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
UOM:
1 * 1 EA
Numéro de catalogue:
(ANTIA304713-100)
Fournisseur:
ANTIBODIES.COM
Description:
Rat monoclonal [91a] antibody to TCP1 alpha/CCTA for WB, ICC/IF, IP and Flow cytometry with samples derived from human, mouse, rat, bovine, rabbit, guinea pig, hamster, canine, porcine, yeast, <i>C. elegans</i>, drosophila and monkey.
UOM:
1 * 1 EA
New Product
Fournisseur:
MEMMERT
Description:
Potential-free contact for combination error message (e.g. supply failure, sensor fault, fuse), Pour: IPP55
Numéro de catalogue:
(730-0109)
Fournisseur:
THERMO OWL SCIENTIFIC
Description:
Ces cuves constituent un moyen simple, pratique et rapide de criblage de plusieurs échantillons dans un seul gel d'agarose. Elles permettent le criblage d'échantillons PCR, les préparations de plasmide, la cartographie de restriction et le clonage.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI25-595)
Fournisseur:
ProSci Inc.
Description:
ATP5G2 is a subunit of mitochondrial ATP synthase. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. ATP5G2 is one of three precursors of subunit c.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene has multiple pseudogenes.
UOM:
1 * 50 µG
Fournisseur:
DWK Life Sciences
Description:
Network Interface is a single-line network adapter for up to 255 R₂P units.
Numéro de catalogue:
(PRSI5871)
Fournisseur:
ProSci Inc.
Description:
ALKBH2 Antibody: The E. coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA; ALKBH2 and ALKBH3 are mammalian homologs of AlkB that catalyze the removal of 1-methyladenine and 3-methylcytosine, modifications that left unchecked could lead to cancerous cells. Mutations in both ALKBH2 and ALKBH3 have been observed in pediatric brain tumors indicating that these proteins are important in the prevention of cancer formation. Like the histone demethylase JMJD1A, ALKBH2 is a non-heme iron enzyme that is inhibited by Nickel ions, suggesting that inhibition of ALKBH2 by Nickel ions may play a role in the development of cancer. Conversely, ALKBH2 mRNA and protein levels are increased glioma cells following Photofrin-mediated photodynamic therapy, an adjuvant therapy in cancer treatment, suggesting that down-regulating ALKBH2 expression in cancer cells may enhance the anti-cancer effectiveness of this treatment.
UOM:
1 * 1 EA
Numéro de catalogue:
(DIDAPOD010045)
Fournisseur:
DIDALAB
Description:
Versatile spectrometer, which can observe the spectrum of any light source: Specific wavelengths, continuous (sunlight, incandescent lamps, candles) and fluorescent spectra.
UOM:
1 * 1 ST
Fournisseur:
ERGOMAT
Description:
Les formes en X DuraStripe®, Supreme V sont parfaites pour guider la circulation et pour les zones de circulation dense. Elles ont également l'avantage d'avoir des bords biseautés afin d'éliminer la plupart des risques de chute et d'impact.
Numéro de catalogue:
(GRSG600249)
Fournisseur:
Greisinger
Description:
The GFTH 200 is a digital hygrometer thermometer with low power consumption, and integrated min-/max- value memory.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI38-205)
Fournisseur:
ProSci Inc.
Description:
Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5623)
Fournisseur:
ProSci Inc.
Description:
LZTR2 Antibody: LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
UOM:
1 * 1 EA
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