Masterflex+Single-use+Flow+Sensor
Fournisseur:
HORIBA
Description:
Électrode, pH
Fournisseur:
KNICK
Description:
Adaptateur pour capteurs industriels de 12 mm avec filetage Pg 13,5
Numéro de catalogue:
(PRSI92-441)
Fournisseur:
ProSci Inc.
Description:
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
UOM:
1 * 50 µG
Fournisseur:
HORIBA
Description:
Ces appareils de mesure sont équipés d'un capteur plan unique qui permet de réaliser des mesures directes, rapides et précises de micro-échantillons d'un volume de 0,12 ml. Ne nécessitant que quelques gouttes, le capteur n'a pas besoin d'être immergé dans l'échantillon.
Fournisseur:
WTW ONLINE
Description:
Sonde à oxygène dissous, Ecoline, TriOxmatic® 690-7, 0 - 60 mg/l ; 0 - 600%, 196 mm, 7 m de câble, avec fiche étanche (IP 65)
Numéro de catalogue:
(PRSI33-198)
Fournisseur:
ProSci Inc.
Description:
Retinol binding protein a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. RBP1 is synthesised by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.
UOM:
1 * 1 EA
New Product
Fournisseur:
VWR Collection
Description:
Ces thermomètres haute précision avec enregistrement de données ont été conçus pour surveiller la température des réfrigérateurs, des congélateurs, des bains-marie, des blocs de chauffage et des incubateurs.
Fournisseur:
SIOEN PERSONAL PROTECTIVE CLOT
Description:
Single-coloured jacket for men, made of 2-layer bonded polyester fleece. Both sides are brushed, one side features an anti-pilling treatment. Can be zipped into different jackets.
Numéro de catalogue:
(PRSI96-169)
Fournisseur:
ProSci Inc.
Description:
CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
UOM:
1 * 1 EA
Fournisseur:
Thermo Orion
Description:
These bench top meters with two measuring channels are designed for accurate and reliable pH, ion concentration, mV, ORP and temperature measurements. Ideal for high throughput pH and ion analysis in the lab.
Fournisseur:
SI Analytics
Description:
When digital IDS sensors are connected to the measuring device, they automatically identify themselves with their serial numbers and type designation and transmit their calibration data to the device.
Numéro de catalogue:
(PRSI4979)
Fournisseur:
ProSci Inc.
Description:
RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI56-003)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI6875)
Fournisseur:
ProSci Inc.
Description:
PTPRD Antibody: PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI38-204)
Fournisseur:
ProSci Inc.
Description:
Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
UOM:
1 * 1 EA
Fournisseur:
IMMUNOLOGIC
Description:
Ki-67 protein is a nuclear protein doublet plays a pivotal role in maintaining cell proliferation. In diagnostic histopathology and cell biology, the antibody has proven valuable for the demonstration of the Ki-67 antigen in normal and neoplastic cells, for example in soft-tissue sarcoma, prostatic adenocarcinoma, and breast carcinoma. It has been confirmed as a very powerful single prognostic factor for overall survival, with highly proliferative cases showing a much poorer outcome than tumors with low proliferation. In breast cancer, the proliferative index measured by Ki-67 immunoreactivity has both prognostic and predictive value.
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