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Single-use+Pressure+Sensor
Numéro de catalogue:
(LOVI194300)
Fournisseur:
Lovibond
Description:
Ideal for field and environmental testing, the TB350 turbidity meter delivers the most reliable measurements for low range to high range samples with unreached accuracy over the complete range. Its new Multipath 90° BLAC® sensor technology makes it the best instrument on the market. Get lab accuracy in a portable solution.
UOM:
1 * 1 ST
Fournisseur:
WITEG LABORTECHNIK GMBH
Description:
These multi-channel pipettes are designed for comfort over long term repetitive pipetting. 8 or 12 identical volumes for titration plates.
Numéro de catalogue:
(PRSI92-527)
Fournisseur:
ProSci Inc.
Description:
LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI76-358)
Fournisseur:
ProSci Inc.
Description:
The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-185)
Fournisseur:
ProSci Inc.
Description:
PECAM-1, or platelet endothelial cell adhesion molecule-1, also called CD31, is made up of six extracellular immunoglobulin-like domains, a single transmembrane domain, and a cytoplasmic domain containing serine and tyrosine residues that when phosphorylated, activate the molecules signaling function. It is expressed on platelets, monocytes, neutrophils, bone marrow macrophage and dendritic cells precursors, and at the intracellular junction of endothelial cells. PECAM-1, on the endothelial lining of blood vessels, helps maintain the vascular barrier. In response to inflammatory mediators, the endothelial pull away from each other allowing fluid, inflammatory cells and proteins into the extravascular space. The inflammatory response fades as adhesion of neighboring cells increase. PECAM-1 also plays an important role in angiogenesis, promoting endothelial cell motility, junctional development and capillary morphogenesis.
UOM:
1 * 1 EA
New Product
Fournisseur:
Thermo Fisher Scientific
Description:
En élastomère thermoplastique (TPE), à l'exception des couvercles en silicone pré-fendus. Pour la fermeture des plaques 96 puits, en particulier des plaques U96 DeepWell™ 1,3 ml et 2,0 ml. Les couvercles en TPE sont résistants au DMSO, à l'éthanol et au méthanol. Les couvercles en silicone sont résistants aux solvants mais ne conviennent pas pour du DMSO à 100%.
Fournisseur:
FINNZYMES REAGENTS
Description:
L'ADN polymérase Phusion® génère des produits de la PCR avec une exactitude et une rapidité inaccessibles avec une seule enzyme, même sur les modèles les plus difficiles. La structure et les caractéristiques de l'ADN polymérase Phusion® haute fidélité en font le meilleur choix pour le clonage et redéfinissent les normes en matière de performance de PCR avec un taux d'erreurs 50 fois plus faible que pour l'ADN polymérase <i>Taq</i> et 6 fois plus faible que pour l'ADN polymérase <i>Pfu</i>. En outre, l'ADN polymérase Phusion® haute fidélité présente une processivité 10 fois supérieure à celle de l'ADN polymérase <i>Pfu</i>.
Numéro de catalogue:
(PRSI28-888)
Fournisseur:
ProSci Inc.
Description:
MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7425)
Fournisseur:
ProSci Inc.
Description:
FGFR3 Antibody: FGFR3 is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. It is required for normal skeleton development and promotes apoptosis in chondrocytes and cancer cell proliferation. FGFR3 protein contains three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain (1,2). It is alternatively spliced to produce three isoforms that are expressed in brain, kidney and testis. Defects in FGFR3 are associated with several diseases, including achondroplasia and hypochondroplasia. Mutations in FGFR3 are also a cause of some bladder and cervical cancers.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-181)
Fournisseur:
ProSci Inc.
Description:
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-753)
Fournisseur:
ProSci Inc.
Description:
Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-635)
Fournisseur:
ProSci Inc.
Description:
Tumour necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR (tumour necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R, as well as its paralog, EDAR, binds the ectodysplasin ligands EDA-A2 and EDA-A1, which are two alternatively spliced forms of the EDA gene. Mutations in the EDA gene are associated with the X-linked form of Hypo hidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.
UOM:
1 * 50 µG
Fournisseur:
EPPENDORF
Description:
Pipettes polyvalentes et ergonomiques avec conception innovante, répondant aux besoins les plus élevés en matière de précision et d'exactitude.
Numéro de catalogue:
(PRSI91-771)
Fournisseur:
ProSci Inc.
Description:
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence, and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
UOM:
1 * 50 µG
Fournisseur:
DWK Life Sciences
Description:
DURAN®, borosilicate glass 3.3, clear.
Numéro de catalogue:
(PRSI91-816)
Fournisseur:
ProSci Inc.
Description:
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration
UOM:
1 * 50 µG
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