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Single-use+Temperature+Sensor
Numéro de catalogue:
(PERCN9303812)
Fournisseur:
PerkinElmer
Description:
Pure Grade standard for AA and ICP-OES.
UOM:
1 * 1 ST
Numéro de catalogue:
(TECN24120-00)
Fournisseur:
Cole-Parmer
Description:
Keep samples cold, clean, and dry.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI51-132)
Fournisseur:
ProSci Inc.
Description:
Reacts with CD95 (Fas/APO-1), a 46 kDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-851)
Fournisseur:
ProSci Inc.
Description:
Human BTN3A3, also known as butyrophilin subfamily 3 member A3 and BTF3, is a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily and BTN/MOG family. The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin domains and an intracellular B30.2 (PRYSPRY) domain. It can be detected in peripheral blood mononuclear cells, T-cells l, spleen and lymphocytes. BTN3A3 plays a role in T-cell responses in the adaptive immune response.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-4114R-CY3)
Fournisseur:
Bioss
Description:
Serine/threonine kinase that plays an essential role in regulating inflammatory responses to viral infection, through the activation of the type I IFN, NF-kappa-B and STAT signaling. Also involved in TNFA and inflammatory cytokines, like Interleukin-1, signaling. Following activation of viral RNA sensors, such as RIG-I-like receptors, associates with DDX3X and phosphorylates interferon regulatory factors (IRFs), IRF3 and IRF7, as well as DDX3X. This activity allows subsequent homodimerization and nuclear translocation of the IRF3 leading to transcriptional activation of pro-inflammatory and antiviral genes including IFNB. In order to establish such an antiviral state, IKBKE forms several different complexes whose composition depends on the type of cell and cellular stimuli. Thus, several scaffolding molecules including IPS1/MAVS, TANK, AZI2/NAP1 or TBKBP1/SINTBAD can be recruited to the IKBKE-containing-complexes. Activated by polyubiquitination in response to TNFA and interleukin-1, regulates the NF-kappa-B signaling pathway through, at least, the phosphorylation of CYLD. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. In addition, is also required for the induction of a subset of ISGs which displays antiviral activity, may be through the phosphorylation of STAT1 at 'Ser-708'. Phosphorylation of STAT1 at 'Ser-708' seems also to promote the assembly and DNA binding of ISGF3 (STAT1:STAT2:IRF9) complexes compared to GAF (STAT1:STAT1) complexes, in this way regulating the balance between type I and type II IFN responses. Protects cells against DNA damage-induced cell death. Also plays an important role in energy balance regulation by sustaining a state of chronic, low-grade inflammation in obesity, wich leads to a negative impact on insulin sensitivity. Phosphorylates AKT1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4114R-CY7)
Fournisseur:
Bioss
Description:
Serine/threonine kinase that plays an essential role in regulating inflammatory responses to viral infection, through the activation of the type I IFN, NF-kappa-B and STAT signaling. Also involved in TNFA and inflammatory cytokines, like Interleukin-1, signaling. Following activation of viral RNA sensors, such as RIG-I-like receptors, associates with DDX3X and phosphorylates interferon regulatory factors (IRFs), IRF3 and IRF7, as well as DDX3X. This activity allows subsequent homodimerization and nuclear translocation of the IRF3 leading to transcriptional activation of pro-inflammatory and antiviral genes including IFNB. In order to establish such an antiviral state, IKBKE forms several different complexes whose composition depends on the type of cell and cellular stimuli. Thus, several scaffolding molecules including IPS1/MAVS, TANK, AZI2/NAP1 or TBKBP1/SINTBAD can be recruited to the IKBKE-containing-complexes. Activated by polyubiquitination in response to TNFA and interleukin-1, regulates the NF-kappa-B signaling pathway through, at least, the phosphorylation of CYLD. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. In addition, is also required for the induction of a subset of ISGs which displays antiviral activity, may be through the phosphorylation of STAT1 at 'Ser-708'. Phosphorylation of STAT1 at 'Ser-708' seems also to promote the assembly and DNA binding of ISGF3 (STAT1:STAT2:IRF9) complexes compared to GAF (STAT1:STAT1) complexes, in this way regulating the balance between type I and type II IFN responses. Protects cells against DNA damage-induced cell death. Also plays an important role in energy balance regulation by sustaining a state of chronic, low-grade inflammation in obesity, wich leads to a negative impact on insulin sensitivity. Phosphorylates AKT1.
UOM:
1 * 100 µl
Fournisseur:
EPPENDORF
Description:
Transition from the tedious process of alternate well pipetting or vessel reformatting with single-channel pipettes to a more efficient manual liquid handling with 384-well plates with one of these starter sets. Each starter set includes a mechanical Eppendorf Research® Plus or electronic Eppendorf Xplorer® Plus multi-channel pipette and a total of 19200 ep Dualfilter T.I.P.S.® 384 filter tips (50 racks of 384 tips) in 'PCR clean and Sterile' grade.
Numéro de catalogue:
(462-0519)
Fournisseur:
GRANT INSTRUMENTS
Description:
Le bain-marie à agitation propose des performances de température et une fiabilité exceptionnelle. Il est parfait pour les applications de base et plus exigeantes dans l'éducation, la recherche, l'industrie agro-alimentaire, la biopharmacie et les sciences de la vie.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-6835R-FITC)
Fournisseur:
Bioss
Description:
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Fournisseur:
Simport Scientific
Description:
These adhesive films, suppliedin sheets, are compatible with most automated adhesive SBS plate sealers.
Numéro de catalogue:
(VIST8066)
Fournisseur:
VISTALAB TECHNOLOGIES
Description:
MLA pipette nozzle insert, white, MLA
UOM:
1 * 10 ST
Numéro de catalogue:
(181-0362)
Fournisseur:
EDWARDS HIGH VACUUM METTLER
Description:
These XDS series pumps are completely oil free, dry scroll and improved on their pumping speeds, combined with lower ultimate pressures, lower power consumption and lower noise. Gas ballast allows for pumping of condensable vapours including water, solvents, dilute acids and bases. It also feature the latest in tip seal technology giving significantly longer life between tip seal changes. Comes with integrated inverter drive with auto sensing voltage input delivers optimised pumping performance. The pumps are completely field serviceable.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI91-569)
Fournisseur:
ProSci Inc.
Description:
alpha-N-Acetylneuraminide alpha-2,8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.
UOM:
1 * 50 µG
Fournisseur:
PerkinElmer
Description:
Lampe à cathode creuse, Lumina™, Pour: Perkin-Elmer instruments, Un élément, chrome
Numéro de catalogue:
(PRSI29-387)
Fournisseur:
ProSci Inc.
Description:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm.
UOM:
1 * 1 EA
Numéro de catalogue:
(732-7509)
Fournisseur:
Corning
Description:
Pour le scellage de microplaques PCR à 96 et 384 puits.
UOM:
1 * 100 ST
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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