mycoplasma+detection
Fournisseur:
Thermo Fisher Scientific
Description:
Les mélanges ABsolute™ qPCR Low ROX sont optimisés pour une utilisation avec des instruments en temps réel qui peuvent détecter avec une sensibilité accrue les colorants à grande longueur d'onde, tels que l'ABI 7500. Le niveau inférieur de ROX facilite encore la normalisation à travers la plaque, tout en préservant la sensibilité du dosage. Les mélanges contiennent tous les composants nécessaires à la réalisation d'une PCR quantitative, à l'exception des matrices et amorces/sondes. Le mélange 2x qPCR contient un tampon de réaction exclusif garantissant des niveaux élevés de sensibilité, de spécificité et de reproductibilité.
Numéro de catalogue:
(PRSI91-775)
Fournisseur:
ProSci Inc.
Description:
Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for beta -neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.
UOM:
1 * 50 µG
Numéro de catalogue:
(BSBTPB9282)
Fournisseur:
BosterBio
Description:
Polyclonal antibody for MAD2/MAD2L1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. MAD2/MAD2L1 information: Molecular Weight: 23510 MW; Subcellular Localization: Nucleus. Chromosome, centromere, kinetochore. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Recruited by MAD1L1 to unattached kinetochores (Probable). Recruited to the nuclear pore complex by TPR during interphase. Recruited to kinetochores in late prometaphase after BUB1, CENPF, BUB1B and CENPE. Kinetochore association requires the presence of NEK2. Kinetochore association is repressed by UBD.
UOM:
1 * 1 EA
Numéro de catalogue:
(BSBTPB9135)
Fournisseur:
BosterBio
Description:
Polyclonal antibody for BUB1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. BUB1 information: Molecular Weight: 46751 MW; Subcellular Localization: Cell membrane. Cytoplasm; Tissue Specificity: Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cytotrophoblasts, and poorly differentiated. colon adenocarcinoma cells found in lymphatics.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI36-119)
Fournisseur:
ProSci Inc.
Description:
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI36-121)
Fournisseur:
ProSci Inc.
Description:
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI36-120)
Fournisseur:
ProSci Inc.
Description:
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-383)
Fournisseur:
ProSci Inc.
Description:
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-340)
Fournisseur:
ProSci Inc.
Description:
PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signalling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-865)
Fournisseur:
ProSci Inc.
Description:
Carcinoembryonic antigen-related cell adhesion molecule 21 is a protein that in humans is encoded by the CEACAM21 gene. It belongs to the immunoglobulin superfamily. CEA family.containing 1 Ig-like C2-type (immunoglobulin-like) domain.It was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
UOM:
1 * 50 µG
Fournisseur:
IMMUNOLOGIC
Description:
Paired box (PAX) gene family whose protein products are transcription factors involved in development. The conserved paired box DNA-binding domain is found in the N-terminal region of Pax proteins. An octomer and homeodomain sequence are conserved in the center of the proteins. The Ser/Thr/ Pro-rich region in the C-terminal portion contains a conserved 100 amino acid transactivating domain. Pax-5 influences the expression of several B-cell-specific genes, such as CD 19 and CD 20. It is expressed primarily in pro-, pre-, and mature B cells, but not in plasma cells. Its mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis. Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis. It has been found to be important in both B cell and nervous system development.
Numéro de catalogue:
(BSBTPA2307)
Fournisseur:
BosterBio
Description:
Polyclonal antibody for TRPC4 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. TRPC4 information: Molecular Weight: 112101 MW; Subcellular Localization: Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Enhanced insertion into the cell membrane after activation of the EGF receptor; Tissue Specificity: Strongly expressed in placenta. Expressed at lower levels in heart, pancreas, kidney and brain. Expressed in endothelial cells. Isoform alpha was found to be the predominant isoform. Isoform beta was not found in pancreas and brain.
UOM:
1 * 1 EA
Numéro de catalogue:
(STMC100-1413)
Fournisseur:
STEMCELL Technologies
Description:
Stimulating T cells with CMV (IE-1) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV (IE-1) peptide pool is a lyophilised mixture of 120 peptides from the immediate early protein IE1 (IE1) of human cytomegalovirus (CMV; strain AD169), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 491 on IE1. CMV IE1 is a transcriptional transactivator and autoregulator (Cherrington and Mocarski). Studies show that IE1 promotes viral transcription by antagonizing histone deacetylation (Nevels <i>et al.</i>) and, along with IE2, may contribute to the survival of CMV-infected cells by blocking tumor necrosis factor alpha (TNF-α)-induced apoptosis (Zhu <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:
1 * 1 PE
New Product
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
IMMUNOLOGIC
Description:
Anti-CD20 (B-cell Pan) reacts with a membrane antigen that is present in B-cells. This antibody recognizes Reed-Sternberg cells, predominant in Hodgkin’s disease, in a minority of cases. Since no staining of histiocytes or plasma cells has been observed and CD20 has not been detected in T-cell malignancies, it is a very strong marker of B-cell lymphomas. Anti-CD20 does not cross-react with non-hematopoetic neoplasms.
Numéro de catalogue:
(PRSI29-037)
Fournisseur:
ProSci Inc.
Description:
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-771)
Fournisseur:
ProSci Inc.
Description:
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence, and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
UOM:
1 * 50 µG
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