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Protéines et Peptides
Numéro de catalogue:
(PRSI4691P)
Fournisseur:
ProSci Inc.
Description:
GDF6 peptide is used for blocking the activity of GDF6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4729P)
Fournisseur:
ProSci Inc.
Description:
MED4 peptide is used for blocking the activity of MED4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4711P)
Fournisseur:
ProSci Inc.
Description:
Hax1a peptide is used for blocking the activity of Hax1a antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3377P)
Fournisseur:
ProSci Inc.
Description:
ECSIT peptide is used for blocking the activity of the ECSIT antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3399P)
Fournisseur:
ProSci Inc.
Description:
IRF3 peptide is used for blocking the activity of IRF3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3401P)
Fournisseur:
ProSci Inc.
Description:
IRF8 peptide is used for blocking the activity of IRF8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3367P)
Fournisseur:
ProSci Inc.
Description:
SIGIRR peptide is used for blocking the activity of the SIGIRR antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-528)
Fournisseur:
ProSci Inc.
Description:
Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the cloned 28 kDa glycoprotein that is related to the p35 chain of IL-12. IL-27 is expressed by monocytes, endothelial cells and dendritic cells. IL-27 binds to and signals through a heterodimeric receptor complex composed of WSX1 (TCCR) and gp130. Evidence suggests IL-27 interacts only with WSX-1. IL-27 has both anti- and proinflammatory properties. As an antiinflammatory, IL-27 seems to induce a general negative feedback program that limits T and NK-T cell activity. At the onset of infection, IL-27 induces an IL-12 receptor on naie CD4+ T cells, making them susceptible to subsequent IL-12 activity (and possible Th1 development). Notably, IL-12 family cytokines are both induced and inhibited by bacterial products. Microbes promote IL-27 secretion through TLR4, and also block IL-27 production via C5a induction.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6977P)
Fournisseur:
ProSci Inc.
Description:
NDFIP1 peptide is used for blocking the activity of NDFIP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-400)
Fournisseur:
ProSci Inc.
Description:
Mouse tumour necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumour suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signalling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-523)
Fournisseur:
ProSci Inc.
Description:
Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rbeta(CRF24), belonging to the class II cytokine receptor family.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6957P)
Fournisseur:
ProSci Inc.
Description:
TCTEX1D4 peptide is used for blocking the activity of TCTEX1D4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6983P)
Fournisseur:
ProSci Inc.
Description:
ANG peptide is used for blocking the activity of ANG antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-177)
Fournisseur:
ProSci Inc.
Description:
Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.It has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-176)
Fournisseur:
ProSci Inc.
Description:
Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. It may repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-180)
Fournisseur:
ProSci Inc.
Description:
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) is a number of the eIF4E-binding protein family. 4EBP1 regulates eIF4E activity by preventing its assembly into the eIF4F complex. 4EBP1 mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Non-phosphorylated 4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E. 4EBP1 is phosphorylated in response to various signals including insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. 4EBP1 has a role in progression of breast neoplasms through cell signaling.
UOM:
1 * 50 µG
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