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Protéines et Peptides


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Protéines et Peptides

Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.


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Numéro de catalogue: (PRSI91-761)

Fournisseur:  ProSci Inc.
Description:   Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI96-884)

Fournisseur:  ProSci Inc.
Description:   Human Epidermal growth factor Receptor 2 (HER2), also called ERBB2, HER-2, HER-2/neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family.
UOM:  1 * 25 µG
Fournisseur:  Shenandoah Biotechnology
Description:   Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
Fournisseur:  Shenandoah Biotechnology
Description:   Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure.
Fournisseur:  Shenandoah Biotechnology
Description:   Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL-1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1β and the independently regulated IL-1α protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
Fournisseur:  Shenandoah Biotechnology
Description:   Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Numéro de catalogue: (A0850.0050)

Fournisseur:  PanReac AppliChem
Description:   Bovine serum albumin (BSA)
UOM:  1 * 50 g
Numéro de catalogue: (J63250.MA)

Fournisseur:  Thermo Scientific
Description:   MG-132
UOM:  1 * 10 mg
Fournisseur:  Shenandoah Biotechnology
Description:   B cell-activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a type II member of the tumor necrosis factor (TNF) superfamily. BAFF is expressed as a transmembrane protein on T cells, macrophages, and dendritic cells. The transmembrane domain of BAFF can also be cleaved to produce a soluble protein fragment.
Fournisseur:  Shenandoah Biotechnology
Description:   Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

Fournisseur:  Merck Millipore (Calbiochem‎)
Description:   Fibrinogen is a soluble plasma glycoprotein that is synthesised in the hepatic parenchymal cells.
UOM:  1 * 1 g
Numéro de catalogue: (650345-1)

Fournisseur:  Merck Millipore (Calbiochem‎)
Description:   Corn trypsin inhibitor
UOM:  1 * 1 mg
Numéro de catalogue: (516483-1MG)

Fournisseur:  Merck Millipore (Calbiochem‎)
Description:   Pepstatin A
UOM:  1 * 1 mg
Numéro de catalogue: (PRSI40-583-25UG)

Fournisseur:  ProSci Inc.
Description:   Rat Recombinant Carboxypeptidase-B (from E. coli)
UOM:  1 * 0,25 mg
Fournisseur:  Shenandoah Biotechnology
Description:   Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN-γ is not cross-reactive with mouse IFN-γ.
Fournisseur:  Shenandoah Biotechnology
Description:   Exodus-2, also known as CCL21 and 6Ckine, is a chemokine that is strongly produced in the human lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration. Exodus-2 also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 proteins share greater than 85% amino acid sequence identity.
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