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Protéines et Peptides
Numéro de catalogue:
(PRSI40-612)
Fournisseur:
ProSci Inc.
Description:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant human VEGF121 is a 28.4 kDa disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI40-605)
Fournisseur:
ProSci Inc.
Description:
Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5651P)
Fournisseur:
ProSci Inc.
Description:
MYBPC2 peptide is used for blocking the activity of MYBPC2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5657P)
Fournisseur:
ProSci Inc.
Description:
EFHD2 peptide is used for blocking the activity of EFHD2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3761P)
Fournisseur:
ProSci Inc.
Description:
LSD1 peptide is used for blocking the activity of LSD1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3741P)
Fournisseur:
ProSci Inc.
Description:
TOLLIP peptide is used for blocking the activity of TOLLIP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5607P)
Fournisseur:
ProSci Inc.
Description:
RSRC1 pepide is used for blocking the activity of RSRC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5663P)
Fournisseur:
ProSci Inc.
Description:
LYRM3 peptide is used for blocking the activity of LYRM3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5667P)
Fournisseur:
ProSci Inc.
Description:
Maelstrom peptide is used for blocking the activity of Maelstrom antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3887P)
Fournisseur:
ProSci Inc.
Description:
PAK2 peptide is used for blocking the activity of PAK2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3871P)
Fournisseur:
ProSci Inc.
Description:
BAG-1 peptide is used for blocking the activity of BAG1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4105P)
Fournisseur:
ProSci Inc.
Description:
Neurotrypsin peptide is used for blocking the activity of Neurotrypsin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4087P)
Fournisseur:
ProSci Inc.
Description:
NogoA peptide is used for blocking the activity of NogoA antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4111P)
Fournisseur:
ProSci Inc.
Description:
ORAI2 peptide is used for blocking the activity of ORAI2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-446)
Fournisseur:
ProSci Inc.
Description:
Interleukin 6 (IL-6) is also known as HGF, BSF2,HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts,endothelial cells,et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes,atherosclerosis, depression,Alzheimer's Disease,systemic,lupus erythematosus,prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.
UOM:
1 * 20 µG
Numéro de catalogue:
(PRSI96-471)
Fournisseur:
ProSci Inc.
Description:
Interleukin 6 receptor (IL6R) is also known as CD126 (Cluster of Differentiation 126) , is a potent pleiotropic cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL6R is a protein complex consisting of a IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit also shared by many other cytokines. The soluble form of IL6R arises from proteolytic cleavage of membrane-bound IL6Rα, and acts agonistically by making the IL6 ligand accessible to the signal transducer gp130. Dysregulated production of IL6 and IL6R are implicated in the pathogenesis of several inflammatory diseases and malignancies such as multiple myeloma, rheumatoid arthritis, or osteoporosis, and it has been reported that a humanised anti-IL6R monoclonal antibody is a promising agent applicable to the therapeutic approach for IL6 driven diseases. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor.
UOM:
1 * 50 µG
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