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Protéines et Peptides
Numéro de catalogue:
(PRSI91-205)
Fournisseur:
ProSci Inc.
Description:
Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Inhibition of GAS7 production in terminally differentiating cultures of embryonic murine cerebullum impedes neurite outgrowth. The hyper-expression of GAS7 may play an major role in the initiation and development of huaman osteosarcoma.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-203)
Fournisseur:
ProSci Inc.
Description:
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat/low-carbohydrate diet.Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6043P)
Fournisseur:
ProSci Inc.
Description:
EFCAB4A peptide is used for blocking the activity of EFCAB4A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6041P)
Fournisseur:
ProSci Inc.
Description:
CXXC4 peptide is used for blocking the activity of CXXC4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-666)
Fournisseur:
ProSci Inc.
Description:
OX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. OX40L–OX40 co-stimulation leads to activation of TNF receptor associated factor (TRAF) 2, 3 and 5. This pathway has been shown to prolong the survival of effector CD4+Th cells as well as contributes to generation of memory T cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-417)
Fournisseur:
ProSci Inc.
Description:
Human Fractalkine (CX3CL1) is a member of the CX3C family of chemokines. Human Fractalkine contains both chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid). The mucin-like stalk permits it to bind to the cell surface.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-363)
Fournisseur:
ProSci Inc.
Description:
IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- gamma ) and tumour necrosis factor-alpha (TNF- alpha) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- gamma . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-830)
Fournisseur:
ProSci Inc.
Description:
Cytokine are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteine. CCL24 diaplays the chemotactic for resting T-lymphocytes and eosinophils. CCL24 has lower chemotatic activity for neutrophils, none for monocytes and activated lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell lines.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4355P)
Fournisseur:
ProSci Inc.
Description:
LGP2 peptide is used for blocking the activity of LGP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4377P)
Fournisseur:
ProSci Inc.
Description:
Nhe-1 peptide is used for blocking the activity of Nhe-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4359P)
Fournisseur:
ProSci Inc.
Description:
TEM1 peptide is used for blocking the activity of TEM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4353P)
Fournisseur:
ProSci Inc.
Description:
LGP2 peptide is used for blocking the activity of LGP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4361P)
Fournisseur:
ProSci Inc.
Description:
TEM2 peptide is used for blocking the activity of TEM2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5817P)
Fournisseur:
ProSci Inc.
Description:
FOXO4 peptide is used for blocking the activity of FOXO4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3775P)
Fournisseur:
ProSci Inc.
Description:
TNFRSF14 peptide is used for blocking activity of TNFRSF14 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6615P)
Fournisseur:
ProSci Inc.
Description:
SPATA18 peptide is used for blocking the activity of SPATA18 antibody.
UOM:
1 * 50 µG
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