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Bioss
Numéro de catalogue:
(BOSSBS-0095R-A350)
Fournisseur:
Bioss
Description:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1851R-FITC)
Fournisseur:
Bioss
Description:
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4893R-A350)
Fournisseur:
Bioss
Description:
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10210R-A647)
Fournisseur:
Bioss
Description:
The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor , gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6728R-HRP)
Fournisseur:
Bioss
Description:
Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6728R-CY3)
Fournisseur:
Bioss
Description:
Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10210R-CY7)
Fournisseur:
Bioss
Description:
The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor , gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4815R-A680)
Fournisseur:
Bioss
Description:
The CD3 complex mediates signal transduction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8500R-A555)
Fournisseur:
Bioss
Description:
Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1208R-CY5)
Fournisseur:
Bioss
Description:
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity). Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8500R-CY5.5)
Fournisseur:
Bioss
Description:
Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4815R-CY5.5)
Fournisseur:
Bioss
Description:
The CD3 complex mediates signal transduction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8500R-A488)
Fournisseur:
Bioss
Description:
Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome is due to mutations in the ALMS1 gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5717R-A350)
Fournisseur:
Bioss
Description:
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0070R-CY5)
Fournisseur:
Bioss
Description:
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles (By similarity). Is a critical central regulator of gonadal function.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1306R-HRP)
Fournisseur:
Bioss
Description:
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
UOM:
1 * 100 µl
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