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Bioss
Numéro de catalogue:
(BOSSBS-1275R-A647)
Fournisseur:
Bioss
Description:
Transcriptional repressor that plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B-cell development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12259R-CY5)
Fournisseur:
Bioss
Description:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9249R-CY3)
Fournisseur:
Bioss
Description:
Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12259R-CY3)
Fournisseur:
Bioss
Description:
Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9249R-A350)
Fournisseur:
Bioss
Description:
Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13589R-A350)
Fournisseur:
Bioss
Description:
ZNF672 is a 452 amino acid nuclear protein that may be involved in transcriptional regulation. Belonging to the Krüppel C2H2-type zinc-finger protein family, ZNF672 contains 14 C2H2-type zinc fingers. ZNF672 exists as two alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 1q44. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome, and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8162R-A680)
Fournisseur:
Bioss
Description:
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organisation and centrosome integrity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3164R-A350)
Fournisseur:
Bioss
Description:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2388R-CY5)
Fournisseur:
Bioss
Description:
Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2388R-A750)
Fournisseur:
Bioss
Description:
Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2388R-CY5.5)
Fournisseur:
Bioss
Description:
Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2388R-CY3)
Fournisseur:
Bioss
Description:
Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0874R-FITC)
Fournisseur:
Bioss
Description:
The DEK gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA which then induces positive supercoils into closed circular DNA, and is also involved during mRNA processing in splice site selection. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6040R-FITC)
Fournisseur:
Bioss
Description:
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0829R-CY7)
Fournisseur:
Bioss
Description:
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0025M-A488)
Fournisseur:
Bioss
Description:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1;PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Three alternative splice variants of PSEN1 have been identified.
UOM:
1 * 100 µl
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