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ProSci Inc.
Numéro de catalogue:
(PRSI57-044)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI61-243)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:2000.
UOM:
1 * 200 µl
New Product
Numéro de catalogue:
(PRSI61-247)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:2000.
UOM:
1 * 200 µl
New Product
Numéro de catalogue:
(PRSI61-220)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:2000.
UOM:
1 * 200 µl
New Product
Numéro de catalogue:
(PRSI33-850)
Fournisseur:
ProSci Inc.
Description:
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-863)
Fournisseur:
ProSci Inc.
Description:
CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [RefSeq].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-851)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a protein of ~50 kDa identified as SOX10. This mAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-900)
Fournisseur:
ProSci Inc.
Description:
This mAb recognises a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-877)
Fournisseur:
ProSci Inc.
Description:
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognises the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. [UniProt].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-870)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons. [RefSeq].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI98-679)
Fournisseur:
ProSci Inc.
Description:
Anti-Cd22 Rat Monoclonal Antibody [clone: 2D6] (PE (Phycoerythrin))
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI98-674)
Fournisseur:
ProSci Inc.
Description:
Anti-Cd19 Mouse Monoclonal Antibody [clone: MB19-1] (APC (Allophycocyanin)-Cy5.5®)
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI98-736)
Fournisseur:
ProSci Inc.
Description:
Anti-Pecam1 Rat Monoclonal Antibody [clone: 390] (APC (Allophycocyanin))
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI57-771)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI57-755)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI33-555)
Fournisseur:
ProSci Inc.
Description:
This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
UOM:
1 * 1 EA
New Product
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