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Protéines et Peptides
Numéro de catalogue:
(PRSI7193P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the center of human TPT1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7191P)
Fournisseur:
ProSci Inc.
Description:
13 amino acids near the carboxy terminus of human PTGDR2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-317)
Fournisseur:
ProSci Inc.
Description:
FAM3C, also called interleukin-like EMT inducer, usually exist in most secretory epithelia. It belongs to the FAM3 family according to their sequence similarities. The up-regulation and/or mislocalization in breast cancer and liver carcinoma cells of FAM3C is strongly correlated with metastasis formation and survival. FAM3C can be involved in retinal laminar formation and promote epithelial to mesenchymal transition.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-331)
Fournisseur:
ProSci Inc.
Description:
Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-320)
Fournisseur:
ProSci Inc.
Description:
IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-329)
Fournisseur:
ProSci Inc.
Description:
The Interferon- alpha/ beta Receptor 1 (IFN- alpha/ beta R1) is a receptor which binds Type I Interferons including Interferon- alpha and - beta . It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2. IFN- alpha/ beta R1, in association with IFN- alpha/ beta R2, is required for propagating antiviral signal transduction triggered by IFN- alpha and IFN- beta . IFN- alpha/ beta R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN- alpha/ beta R2. Ligands associate with IFN- alpha/ beta R2, and this complex subsequently forms a stable ternary assembly with IFN- alpha/ beta R1. IFN- alpha/ beta R1 also associates with IFN- gamma R2 even in the absence of IFN- gamma stimulation. Human IFN- alpha/ beta R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand. Interferon stimulation results in an immunologic response that is especially associated with viruses.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-065)
Fournisseur:
ProSci Inc.
Description:
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-070)
Fournisseur:
ProSci Inc.
Description:
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-639)
Fournisseur:
ProSci Inc.
Description:
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and integrins to regulate cell proliferation, differentiation, adhesion, migration, angiogenesis, and survival. CCN3 is firstly characterised as a promoter of progenitor activity of human hematopoietic stem cells, as knockdown of CCN3 can abrogate the function of primitive progenitors. Recent studies showed that CCN3 is also actively involved in the process of wound healing. CCN3 is highly expressed in granulation tissues of cutaneous wounds and capable of inducing synthetic responses of fibroblasts.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2337P)
Fournisseur:
ProSci Inc.
Description:
IKAP peptide is used for blocking activity of IKAP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2355P)
Fournisseur:
ProSci Inc.
Description:
IRAK-M peptide is used for blocking the activity of IRAK-M antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2327P)
Fournisseur:
ProSci Inc.
Description:
Caspase-12 peptide is used for blocking the activity of caspase-12 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5567P)
Fournisseur:
ProSci Inc.
Description:
SYNGR3 peptide is used for blocking the activity of SYNGR3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-459)
Fournisseur:
ProSci Inc.
Description:
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-200)
Fournisseur:
ProSci Inc.
Description:
Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulating the activity of ribosomal subunits 43S, 48S and 40S. EIF1B enables 43S ribosomal complexes to distinguish between cognate and near-cognate initiation codons, perceiving the nucleotide content of initiation codons.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4657P)
Fournisseur:
ProSci Inc.
Description:
EVER2 peptide is used for blocking the activity of EVER2 antibody.
UOM:
1 * 50 µG
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