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Protéines et Peptides
Fournisseur:
Shenandoah Biotechnology
Description:
Fibroblast growth factor 10 (FGF-10) is a growth factor that is important during embryonic development, especially during lung, limb, brain, heart, and kidney morphogenesis.FGF-10 is expressed in mesenchymal cells and facilitates epithelial-mesenchymal signaling through binding the epithelially expressed FGF receptor 2b (FGFR2b). FGF-10 also functions as a mitogen for keratinising epidermal cells, and induces the migration and invasion of cancer cells.
Numéro de catalogue:
(J63131.MA)
Fournisseur:
Thermo Scientific
Description:
An endogenous vasodilator peptide
UOM:
1 * 10 mg
Numéro de catalogue:
(J62102.MB)
Numéro de catalogue:
(J62919.MB)
Numéro de catalogue:
(PRSI91-960)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN- gamma by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5383P)
Fournisseur:
ProSci Inc.
Description:
JMJD6 peptide is used for blocking the activity of JMJD6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-121)
Fournisseur:
ProSci Inc.
Description:
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP7 is predominately expressed in brain and neural tissues. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. FABP7 plays a critical role in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. FABP7 is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-126)
Fournisseur:
ProSci Inc.
Description:
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions, which suggested a role for grancalcin in granule-membrane fusion and degranulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-235)
Fournisseur:
ProSci Inc.
Description:
IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-228)
Fournisseur:
ProSci Inc.
Description:
BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-223)
Fournisseur:
ProSci Inc.
Description:
RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of breast cancer.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-224)
Fournisseur:
ProSci Inc.
Description:
LIGHT (HVEML; CD258) is a cytokine that binds to TNFRSF3/LTBR. It activates NF-kappaB, stimulates the proliferation of T cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI2237P)
Fournisseur:
ProSci Inc.
Description:
Survivin peptide is used for blocking the activity of Survivin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3751P)
Fournisseur:
ProSci Inc.
Description:
IL-32 peptide is used for blocking the activity of IL-32 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3739P)
Fournisseur:
ProSci Inc.
Description:
TLR9 peptide is used for blocking the activity of TLR9 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3757P)
Fournisseur:
ProSci Inc.
Description:
DDX3 peptide is used for blocking the activity of DDX3 antibody.
UOM:
1 * 50 µG
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