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Protéines et Peptides
Fournisseur:
Shenandoah Biotechnology
Description:
Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic binds heparin in order to signal through fibroblast growth factor (FGF) receptor tyrosine kinases.
Fournisseur:
Shenandoah Biotechnology
Description:
Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.
Numéro de catalogue:
(PRSI6755P)
Fournisseur:
ProSci Inc.
Description:
TSHZ1 peptide is used for blocking the activity of TSHZ1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-223)
Fournisseur:
ProSci Inc.
Description:
Cathepsin B (CTSB) is also known as APP secretase (APPS) and CPSB, is an enzymatic protein belonging to the peptidase C1 family. Cathepsin B / CTSB is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme. The catalytic activity of Cathepsin B / APPS contains: Hydrolysis of proteins with broad specificity for peptide bonds; Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L); In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. As a thiol protease, cathepsin B / CPSB is believed to participate in intracellular degradation and turnover of proteins and has also been implicated in tumor invasion and metastasis. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-231)
Fournisseur:
ProSci Inc.
Description:
Human recombinant Car (from HEK293 cells)
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-735)
Fournisseur:
ProSci Inc.
Description:
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7421P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the amino terminus of human Bim EL.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7389P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the carboxy terminus of human DAP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7383P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the center of human TRIM24.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7417P)
Fournisseur:
ProSci Inc.
Description:
18 amino acids near the center of La Crosse Virus Nucleocapsid.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-247)
Fournisseur:
ProSci Inc.
Description:
Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-352)
Fournisseur:
ProSci Inc.
Description:
Signal Regulatory Protein alpha (SIRP alpha) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRP alpha contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRP alpha can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRP alpha acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRP alpha shows adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. SIRP alpha engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis, mast cell activation and dendritic cell activation
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3493P)
Fournisseur:
ProSci Inc.
Description:
Raptor peptide is used for blocking the activity of the Raptor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3477P)
Fournisseur:
ProSci Inc.
Description:
Mcl-1 peptide is used for blocking the activity of Mcl-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-343)
Fournisseur:
ProSci Inc.
Description:
Human recombinant GCSFR (from HEK293 cells)
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI3623P)
Fournisseur:
ProSci Inc.
Description:
CRMP1 peptide is used for blocking the activity of CRMP1 antibody.
UOM:
1 * 50 µG
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