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Protéines et Peptides
Numéro de catalogue:
(PRSI7267P)
Fournisseur:
ProSci Inc.
Description:
19 amino acid peptide near the carboxy terminus of human PTRF.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7279P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the center of human MOSPD1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7271P)
Fournisseur:
ProSci Inc.
Description:
16 amino acids near the center of human Nucleobindin-2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-282)
Fournisseur:
ProSci Inc.
Description:
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-456)
Fournisseur:
ProSci Inc.
Description:
TIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is one newly discovered immune receptor on some percentage of T cells and Natural Killer Cells(NK). It is also identified as WUCAM and Vstm3. TIGIT could bind to CD155(PVR) on dendritic cells(DCs), macrophages, etc. with high affinity, and also to CD112(PVRL2) with lower affinity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2289P)
Fournisseur:
ProSci Inc.
Description:
Bnip3L peptide is used for blocking the activity of Bnip3L antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5953P)
Fournisseur:
ProSci Inc.
Description:
NOD5 peptide is used for blocking the activity of NOD5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-454)
Fournisseur:
ProSci Inc.
Description:
LY86 is a protein that in humans is encoded by the LY86 gene, which May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-469)
Fournisseur:
ProSci Inc.
Description:
V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-455)
Fournisseur:
ProSci Inc.
Description:
Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6719P)
Fournisseur:
ProSci Inc.
Description:
MLIP peptide is used for blocking the activity of MLIP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-292)
Fournisseur:
ProSci Inc.
Description:
Notch signalling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signalling is also involved in cellular processes through-out adulthood. Signalling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-299)
Fournisseur:
ProSci Inc.
Description:
Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-290)
Fournisseur:
ProSci Inc.
Description:
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, haematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signalling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6047P)
Fournisseur:
ProSci Inc.
Description:
LMBRD1 peptide is used for blocking the activity of LMBRD1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6271P)
Fournisseur:
ProSci Inc.
Description:
ApoA5 peptide is used for blocking the activity of ApoA5 antibody.
UOM:
1 * 50 µG
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