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Antilichamen
Itemnummer:
(ENZOADIKAMCC006E)
Leverancier:
ENZO LIFE SCIENCES
Omschrijving:
Centromere protein A (CENP-A), a 17-19 kDa centromere-specific histone variant, is 62% identical to the carboxy-terminal domain of histone H3. In the presence of DNA, CENP-A forms an octameric complex with histones H4, H2A, and H2B. CENP-A defines active centromere regions by forming centromere-specific nucleosomes on which kinetochores are assembled. CENP-A resides specifically in the inner plate of the kinetochore, and is essential for kinetochore targeting of CENP-C and other kinetochore components. CENP-A is required for nucleosomal packaging of centromeric DNA at interphase.
UOM:
1 * 1 EA
New Product
Itemnummer:
(ENZOBMLSA4680100)
Leverancier:
ENZO LIFE SCIENCES
Omschrijving:
Host: Mouse, Isotype: IgG1
UOM:
1 * 1 EA
New Product
Itemnummer:
(ENZOBMLSA4930015)
Leverancier:
ENZO LIFE SCIENCES
Omschrijving:
Host: Mouse
UOM:
1 * 1 EA
New Product
Itemnummer:
(ENZOBMLSA4770100)
Leverancier:
ENZO LIFE SCIENCES
Omschrijving:
Host: Rabbit
UOM:
1 * 100 µl
New Product
Itemnummer:
(PRSI11-015)
Leverancier:
ProSci Inc.
Omschrijving:
Anti-Spike Glycoprotein antibody MGA
UOM:
1 * 0,1 mg
New Product
Itemnummer:
(PRSI10-998)
Leverancier:
ProSci Inc.
Omschrijving:
Anti-HLX10 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Itemnummer:
(PRSI11-011)
Leverancier:
ProSci Inc.
Omschrijving:
Anti-Basiliximab;CHI-621/SDZ-CHI-621 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Itemnummer:
(PRSI11-003)
Leverancier:
ProSci Inc.
Omschrijving:
Anti-BAY-1834942 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Itemnummer:
(BOSSBS-1413R-CY5)
Leverancier:
Bioss
Omschrijving:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
UOM:
1 * 100 µl
Itemnummer:
(ENZOADI915062100)
Leverancier:
ENZO LIFE SCIENCES
Omschrijving:
Metabolism of inositol phospholipids by intracellular signaling mediators is fundamental to signal transduction in eukaryotic cells. PI-4,5-P2 (Phosphatidylinositol 4,5-bisphosphate; PIP2) can be synthesized by phosphorylation of PI-4-P by type I phosphatidylinositol phosphate kinase (PIP5K I), or phosphorylation of PI-5-P by type II PIPK (PIP4K II). PI-4,5-P2 regulation of cellular calcium levels involves its hydrolysis by Phospholipase C (PLC) to produce inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG), which serve as second messengers in the import of calcium via IP3-sensitive ion channels and in the activation of PKC, respectively.
UOM:
1 * 1 EA
New Product
Itemnummer:
(ENZOADI915043100)
Leverancier:
ENZO LIFE SCIENCES
Omschrijving:
15-deoxy-Δ12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Δ12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the γ isoform of the peroxisome proliferators-activated receptor (PPAR-γ). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-γ-independent mechanism mediated by the generation of reactive oxygen species (ROS).
UOM:
1 * 100 µl
New Product
Itemnummer:
(BSENM-1723-100)
Leverancier:
Biosensis
Omschrijving:
TrkA is a member of the neurotrophic tyrosine kinase receptor family. It is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkA is required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). TrkA leads to cell differentiations and may play a role in specifying sensory neuron subtypes. It has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Cell membrane; single-pass type I membrane protein. Endocytosed to the endosomes upon treatment of cells with NGF. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. Both isoforms have similar biological properties. TISSUE SPECIFICITY: Isoform TrkA-II is primarily expressed in neuronal cells. Isoform TrkA-I is found in non-neuronal tissues. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutalating behaviour, mental retardation and cancer (Reference: www.uniprot.com).
UOM:
1 * 1 EA
Leverancier:
Tonbo Biosciences
Omschrijving:
The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Itemnummer:
(25-4724-U100)
Leverancier:
Tonbo Biosciences
Omschrijving:
The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.
UOM:
1 * 1 EA
Itemnummer:
(ORIGTA307966)
Leverancier:
OriGene
Omschrijving:
Anti-NDUFV2 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(GENSA02283-200)
Leverancier:
Genscript
Omschrijving:
This product is specific for scFvs in different species (humanised, mouse) and different orders (VH-linker-VL, VL-linker-VH). It can also recognise various forms of scFv-based bispecific antibodies, such as DART, BITE, TandAbs, IgG(H)-scFv2 and scFv-Fab-Fc.
UOM:
1 * 200 µl
New Product
Bel voor prijs
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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