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Antilichamen
Itemnummer:
(BOSSBS-11887R-CY3)
Leverancier:
Bioss
Omschrijving:
Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-4216R-CY5)
Leverancier:
Bioss
Omschrijving:
Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8325R-A350)
Leverancier:
Bioss
Omschrijving:
Cell cycle progression is subject to arrest at G1 and G2 checkpoints in response to DNA damage, presumably to allow time for DNA repair prior to entry into S and M phase, respectively. The p53 tumor suppressor is required for one such G1 checkpoint and functions to upregulate expression of GADD 45 and the mitotic inhibitory protein p21. GADD 45 stimulates DNA excision repair in vitro and inhibits entry of cells into S phase, and it apparently acts in concert with GADD 153 in inducing growth arrest. A related DNA-damage inducible gene, GADD 34 synergizes with GADD 45 or GADD 153 in suppressing cell growth. PEG-3 (progression elevated gene-3) shares significant homology with GADD 34 and is inducible by DNA damage. An additional GADD related gene, PA26, is a possible target of p53. Three isoforms of PA26 have been identified as PA26-T1, PA26-T2 and PA26-T3.
UOM:
1 * 100 µl
Itemnummer:
(USBI037543-PE)
Leverancier:
US Biological
Omschrijving:
Anti-KLHDC8B Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBIA0857-25A)
Leverancier:
US Biological
Omschrijving:
Anti-CREB3L4 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Itemnummer:
(USBIA0856-10D)
Leverancier:
US Biological
Omschrijving:
Anti-ACVR2B Mouse Monoclonal Antibody [clone: 9H22]
UOM:
1 * 1 EA
Itemnummer:
(USBIA0857-06A)
Leverancier:
US Biological
Omschrijving:
Anti-AIB 1 Mouse Monoclonal Antibody [clone: 6D102]
UOM:
1 * 1 EA
Itemnummer:
(BOSSBS-7757R-A555)
Leverancier:
Bioss
Omschrijving:
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7757R-A488)
Leverancier:
Bioss
Omschrijving:
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
UOM:
1 * 100 µl
Itemnummer:
(IMMRIR1419)
Leverancier:
ImmunoReagents
Omschrijving:
ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy. Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.
UOM:
1 * 1 mg
Itemnummer:
(IMMRIR1414)
Leverancier:
ImmunoReagents
Omschrijving:
ImmunoReagents’ Horseradish Peroxidase (HRP) antibody conjugates are the most popular conjugates due to their high level of sensitivity, stability, and low costs. HRP conjugates are an ideal choice for use in ELISA, Immunohistochemistry (IHC), and Western blotting experiments.
UOM:
1 * 1 mg
Itemnummer:
(IMMRIR1409)
Leverancier:
ImmunoReagents
Omschrijving:
The ImmunoReagents' DyLight® 800 conjugates uses a near-IR fluorphore that is invisible to the naked eye but increases the staining options when using infrared imaging systems. DyLight® 800 has spectral properties that are very similar to other near-IR dyes, including Alexa Fluor 790 and IRDye 800, and has high solubility for maximal incorporation of the dye into the biomolecule of interest. Excitation/Emission = 777 nm/794 nm Emission Colour = Near IR (Similar Dyes: Alexa Fluor 790, IRDye 800).
UOM:
1 * 1 mg
Itemnummer:
(IMMRIR1400)
Leverancier:
ImmunoReagents
Omschrijving:
ImmunoReagents’ Horseradish Peroxidase (HRP) antibody conjugates are the most popular conjugates due to their high level of sensitivity, stability, and low costs. HRP conjugates are an ideal choice for use in ELISA, Immunohistochemistry (IHC), and Western blotting experiments.
UOM:
1 * 0,5 mg
Itemnummer:
(IMMRIR1658)
Leverancier:
ImmunoReagents
Omschrijving:
The ImmunoReagents DyLight® 550 conjugates provide vibrant orange-to-red fluorescence with better performance than other rhodamine derivatives, including Alexa Fluor 555, TRITC and Cy3 for fluorescent applications. DyLight® 550 conjugates have tight excitation/emission spectra that are ideal for multicolor applications. DyLight® 550 conjugated secondary antibodies are used in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 562 nm / 576 nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, TRITC).
UOM:
1 * 1 mg
Itemnummer:
(IMMRIR1415)
Leverancier:
ImmunoReagents
Omschrijving:
ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy. Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.
UOM:
1 * 0,5 mg
Itemnummer:
(IMMRIR1385)
Leverancier:
ImmunoReagents
Omschrijving:
ImmunoReagents’ FITC Conjugates are used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. Fluorescein is typically excited by the 488 nm line of an argon laser, and emission is collected at 518 nm. FITC antibody conjugates are yellow-orange in Colour but emit a yellow-green Colour upon Em 518 nm. FITC antibody conjugates are sensitive to light. The typical FITC to antibody ratio (F/P) is >4.0 Excitation/Emission = 494 nm/518 nm Emission Colour = Green (Similar Dyes: Alexa Fluor 488, Cy2, DyLight ® 488).
UOM:
1 * 2 mg
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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