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Antilichamen
Itemnummer:
(BOSSBS-12393R)
Leverancier:
Bioss
Omschrijving:
Anti-BCL9 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-12421R)
Leverancier:
Bioss
Omschrijving:
14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 b, g, e, z, h, q and s. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins; by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity, and facilitation of protein modification. Loss of expression contributes to a vast array of pathogenic cellular activities.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-12392R)
Leverancier:
Bioss
Omschrijving:
Anti-AES Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-12428R)
Leverancier:
Bioss
Omschrijving:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-12430R)
Leverancier:
Bioss
Omschrijving:
DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11756R)
Leverancier:
Bioss
Omschrijving:
Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters. Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids. Sulfamidase, also known as HSS, SFMD, MPS3A or SGSH, is a 502 amino acid lysosome that belongs to the sulfatase family. It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate. Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate. Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15339R)
Leverancier:
Bioss
Omschrijving:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf7 gene product has been provisionally designated C9orf7 pending further characterization.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15335R)
Leverancier:
Bioss
Omschrijving:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf62 gene product has been provisionally designated C9orf62 pending further characterization.
UOM:
1 * 100 µl
Itemnummer:
(USBI036210-APC)
Leverancier:
US Biological
Omschrijving:
Anti-GPN1 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Itemnummer:
(USBI036210-AP)
Leverancier:
US Biological
Omschrijving:
Anti-GPN1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(USBI042902-PE)
Leverancier:
US Biological
Omschrijving:
Anti-TMEM55B Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBI042903-AP)
Leverancier:
US Biological
Omschrijving:
Anti-TM6SF1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(USBI168519)
Leverancier:
US Biological
Omschrijving:
Anti-SPANX, pan Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Itemnummer:
(USBI042899-APC)
Leverancier:
US Biological
Omschrijving:
Anti-TM4SF1 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Itemnummer:
(USBI037485-FITC)
Leverancier:
US Biological
Omschrijving:
Anti-KIT Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Itemnummer:
(USBIA1334-76A)
Leverancier:
US Biological
Omschrijving:
Anti-AKR7A2 Rabbit Polyclonal Antibody
UOM:
1 * 200 µl
Bel voor prijs
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
Bijkomende documentatie kan noodzakelijk zijn voor dit item. Een VWR-verantwoordelijke zal contact opnemen met u indien nodig.
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