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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI92-425)
Fournisseur:
ProSci Inc.
Description:
Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Ephrin-B1 is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighboring cells. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-307)
Fournisseur:
ProSci Inc.
Description:
TCF25 acts as a transcriptional repressor. It has been shown to repress transcription of SRF in vitro and so may play a role in heart development.
UOM:
1 * 1 EA
Fournisseur:
Agilent
Description:
DB-5.625 is specially processed to exhibit excellent inertness for EPA semivolatile methods 625, 1625, 8270, and CLP protocols.
Numéro de catalogue:
(17-0430-01)
Fournisseur:
Cytiva
Description:
CNBr-activated Sepharose™ 4B is pre-activated media used for coupling antibodies or other large proteins containing -NH₂ groups to the Sepharose™ media, by the cyanogen bromide method, without an intermediate spacer arm.
UOM:
1 * 15 g
Numéro de catalogue:
(AATB3403)
Fournisseur:
AAT BIOQUEST
Description:
ReadiLeave™ Reversible (RLR) Biotin is a newly developed biotin derivative that has significantly reduced affinity to avidin (including streptavidin) to make the binding of RLR biotin and streptavidin readily reversible when needed.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB3405)
Fournisseur:
AAT BIOQUEST
Description:
ReadiLeave™ Reversible (RLR) Biotin is a newly developed biotin derivative that has significantly reduced affinity to avidin (including streptavidin) to make the binding of RLR biotin and streptavidin readily reversible when needed.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI92-570)
Fournisseur:
ProSci Inc.
Description:
Ectodysplasin A receptor (EDAR) is a type I transmembrane protein of the TNF- alpha receptor superfamily which plays a key role in ectodermal differentiation. EDAR was encoded by the mouse down less gene and defective in human dominant and recessive forms of autosomal hypo hidrotic ectodermal dysplasia (EDA) syndrome. The extracellular domain of EDAR contains 14 cysteine residues, six of which approximate the TNFRSF cysteine-rich region, the cytoplasmic domain contains a region with homology to the death domains found in other TNFRSF members. EDAR has been suggested to be an early and important promoter of placode development in all ectodermal organs, such as uch as hair follicles, teeth and sweat glands. EDA-A1, the A1 isoform of EDA, is the EDAR ligand. EDA and EDA are implicated in appendage development by the cloning of a gene underlying hypo hidrotic ectodermal dysplasia (HED) in mouse and human. HED is Characterised by agenesis or malformation of ectoderm-derived appendages, such as teeth, sweat glands and hair follicles, while the skin itself develops normally.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5495)
Fournisseur:
ProSci Inc.
Description:
SIPA1L3 Antibody: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI50-264)
Fournisseur:
ProSci Inc.
Description:
Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).
UOM:
1 * 100 µl
Numéro de catalogue:
(STMC100-1411)
Fournisseur:
STEMCELL Technologies
Description:
Human (Actin) peptide pool is a lyophilised mixture of 92 peptides from human actin, alpha skeletal muscle, and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 377 on actin. It is frequently used as a negative control. Actin, alpha skeletal muscle, is part of the highly conserved actin protein family and is the predominant isoform found in adult skeletal muscle (Laing <i>et al.</i>). Peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:
1 * 1 UO
New Product
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Fournisseur:
AAT BIOQUEST
Description:
ReadiLeave™ Reversible (RLR) Biotin is a newly developed biotin derivative that has significantly reduced affinity to avidin (including streptavidin) to make the binding of RLR biotin and streptavidin readily reversible when needed.
Numéro de catalogue:
(BOSSBS-1531R-HRP)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB21224)
Fournisseur:
AAT BIOQUEST
Description:
Protonex™ Green 500 PEG12 maleimide is a thiol-reactive, pH-sensitive fluorophore specifically designed for developing pH-responsive bioconjugates to investigate processes such as antibody internalization, endocytosis, and phagocytosis in live cells.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI25-932)
Fournisseur:
ProSci Inc.
Description:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters.Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-890)
Fournisseur:
ProSci Inc.
Description:
SLC2A9 is a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. SLC2A9 may play a role in the development and survival of chondrocytes in cartilage matrices.This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.
UOM:
1 * 50 µG
Fournisseur:
Restek
Description:
These application-specific columns with proprietary crossbond phases are suitable for organophosphorus pesticides and best column combination for US EPA Method 8141.
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