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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI6319)
Fournisseur:
ProSci Inc.
Description:
SGK1 Antibody: Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI56-625)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin and may function in renal tubular development and function. Mutations in this gene are associated with nephronophthisis type 3. Multiple splice variants have been described but their full-length nature has not been determined.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI6183)
Fournisseur:
ProSci Inc.
Description:
VPS39 Antibody: VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.
UOM:
1 * 1 EA
Numéro de catalogue:
(705-0732)
Fournisseur:
Thermo Orion
Description:
Measure common colorimetric water and wastewater parameters using the Orion™ AQUAfast™ AQ3700 colorimeter with 90 preprogrammed methods, automatic selection of 6 LED wavelengths and timer. Methods include total nitrogen and total phosphate nutrient testing or create up to 10 custom methods using 2-14 standards and blank.
UOM:
1 * 1 ST
Numéro de catalogue:
(USBI135533)
Fournisseur:
US Biological
Description:
Anti-ZDHHC13 Mouse Monoclonal Antibody [clone: 2A4]
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-193)
Fournisseur:
ProSci Inc.
Description:
bHLH proteins are essential for neurogenesis, myogenesis, haematopoiesis and sex determination. HES1 (Hairy and Enhancer of Split 1) is a basic Helix-Loop-Helix (bHLH) transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signalling plays both oncogenic and tumour suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukaemia (ALL), where Notch activation promotes leukemogenesis, induction of Notch signalling in B cell ALL (B-ALL) leads to growth arrest and apoptosis. The Notch target HES1 is sufficient to reproduce this tumour suppressor phenotype in B-ALL by interacting and activating PARP-1 and regulating proapoptotic signals.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-107)
Fournisseur:
ProSci Inc.
Description:
Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI56-201)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-262)
Fournisseur:
ProSci Inc.
Description:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-613)
Fournisseur:
ProSci Inc.
Description:
Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors (By similarity).
UOM:
1 * 400 µl
New Product
Fournisseur:
Thermo Orion
Description:
RS232 cable for method uploads and data downloads, Pour: Multi-parameter colorimeters, Orion™ AQUAfast™ AQ3700 and AQ4000
Numéro de catalogue:
(PRSI32-129)
Fournisseur:
ProSci Inc.
Description:
The CD19 antigen (95 kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.
UOM:
1 * 1 EA
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