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Numéro de catalogue: (PRSI6443)

Fournisseur:  ProSci Inc.
Description:   EIG121 Antibody: EIG121 (Estrogen-induced gene 121 protein) is thought to play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. It belongs to the UPF0577 family. It is a 1013 amino acid single-pass transmembrane protein that, though expressed in normal endometrium, is overexpressed in endometriod tumors. As an evolutionarily conserved gene, EIG121 is also expressed during early xenopus development, showing maximum expression at the gastrula stage.
UOM:  1 * 1 EA

Fournisseur:  ProSci Inc.
Description:   High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-890)

Fournisseur:  ProSci Inc.
Description:   CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-706)

Fournisseur:  ProSci Inc.
Description:   Leucine-Rich Repeat Transmembrane Protein FLRT3 (FLRT3) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. Proteins in this family play an role in cell adhesion and/or receptor signalling. FLRT3 is a single-pass type I membrane protein and contains one fibronectin type-III domain, ten LRR (leucine-rich) repeats, one LRRCT domain, and one LRRNT domain. FLRT3 may have a function in cell adhesion and/or receptor signaling. FLRT3 may regulate cellular adhesion between the epithelial apical ridge and the underlying mesenchyme and in establishing the dorso-ventral position of the ridge.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI92-337)

Fournisseur:  ProSci Inc.
Description:   Cytotoxic T-lymphocyte protein 4, is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-327)

Fournisseur:  ProSci Inc.
Description:   T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
UOM:  1 * 50 µG
Fournisseur:  Corning
Description:   Axygen® ImpermaMat sealing mats minimize evaporation in a wide range of temperatures in PCR and storage applications. ImpermaMats are chemically resistant, reusable sealing mats, that provide a high degree of confidence.
Fournisseur:  Portwest
Description:   This versatile coat features a concealed stud front, two lower patch pockets, and a single chest pocket.
Numéro de catalogue: (PRSI29-226)

Fournisseur:  ProSci Inc.
Description:   RBMS3 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2 (I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI30-069)

Fournisseur:  ProSci Inc.
Description:   TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
UOM:  1 * 50 µG
Fournisseur:  ASYNT
Description:   Adaptateurs pour DrySyn COOL et DrySyn Multi COOL, permettant un raccordement aux tuyaux isolés M16
UOM:  1 * 2 ST
Numéro de catalogue: (HEWL8500-6936)

Fournisseur:  Agilent
Description:   Standard de bismuth, 10 mg/L, Bismuth, Applications: Étalons ICP
UOM:  1 * 1 ST
Numéro de catalogue: (PRSI92-188)

Fournisseur:  ProSci Inc.
Description:   Chloride intracellular channel protein 3 (CLIC3) is encoded by the CLIC3 gene. CLIC3 is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain and one GST N-terminal domain. Chloride intracellular channel protein 3 high expressed in the placental, lung and heart, low expressed in skeletal muscle, kidney and pancreas. Chloride intracellular channel protein 3 can insert into membranes and forms chloride ion channels, may participate in cellular growth control.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-543)

Fournisseur:  ProSci Inc.
Description:   Protocadherin-10 (PCDH10) is a single-pass type I membrane protein that contains six extracellular cadherin domains, one transmembrane domain and one cytoplasmic tail differing from those of the classical cadherins. As a potential calcium-dependent cell-adhesion neuronal receptor, it may plays a role in the establishment and function of specific cell-cell connections in the brain. PCDH10 moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tested tissues.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-514)

Fournisseur:  ProSci Inc.
Description:   CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 amino acid transmembrane segment, and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
UOM:  1 * 50 µG
Numéro de catalogue: (HAMI67098-01)

Fournisseur:  HAMILTON BONADUZ
Description:   Sonde manuelle avec pointe à usage unique Microlab 300, kit de tubes, comprenant 5 ferrules, 5 anneaux en acier inoxydable, 5 fixations, 5 clapets de décharge, 12 tubes indicateurs et une pointe de sonde, Pour: Microlab 300
UOM:  1 * 1 ST
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