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Single-use+Temperature+Sensor
Numéro de catalogue:
(PRSI25-230)
Fournisseur:
ProSci Inc.
Description:
CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-776)
Fournisseur:
ProSci Inc.
Description:
KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
UOM:
1 * 50 µG
Fournisseur:
LIEFERSERVICE UND LOGISTIK GMB
Description:
The Super-Birki anti-static clog models are fitted with replaceable anti-static integrated insoles. Birki anti-static model has an integrated insole made of a single piece of flexible anti-static blended foam.
Numéro de catalogue:
(735-0190)
Fournisseur:
Thermo Fisher Scientific
Description:
Designed to protect microplate well contents by facilitating a tight seal.
UOM:
1 * 100 ST
Numéro de catalogue:
(PRSI91-898)
Fournisseur:
ProSci Inc.
Description:
Mouse Cathepsin L is a lysosomal cysteine proteinase which is a member of the peptidase C1 family. This protein is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Cathepsin L plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. Cathepsin L has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria.
UOM:
1 * 50 µG
Numéro de catalogue:
(118-0416)
Fournisseur:
BROEN-LAB
Description:
Douches oculaires pour montage sur table. Avec une ou deux têtes de douche 45°.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI92-445)
Fournisseur:
ProSci Inc.
Description:
tumour necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is the ligand for CD134 and is expressed on such cells as DC2s enabling amplification of Th2 cell differentiation. It is a cytokine that binds to TNFRSF4, Co-stimulates T-cell proliferation and cytokine production. It has been found association with systemic lupus erythematosus, No association with occurrence of atherosclerosis.
UOM:
1 * 50 µG
Fournisseur:
Brady
Description:
PermaSleeve® HT PVDF wire marker sleeve specifically designed for high temperature and low vacuum outgassing applications.
Numéro de catalogue:
(PRSI91-818)
Fournisseur:
ProSci Inc.
Description:
IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-591)
Fournisseur:
ProSci Inc.
Description:
Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterosygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
UOM:
1 * 50 µG
Numéro de catalogue:
(735-0187)
Fournisseur:
Thermo Fisher Scientific
Description:
Joints adhésifs pour microplaques. 100 feuilles par paquet.
UOM:
1 * 100 ST
Fournisseur:
GLASWARENFABRIK KARL HECHT
Description:
Capillaires de précision, pour pipettes Assipettor fixes, 5 μl
Fournisseur:
Thermo Fisher Scientific
Description:
These columns can resolve protein isoforms that differ by a single charged residue. A thin, hydrophilic layer prevents unwanted secondary interactions. The grafted anion exchange surface provides pH based selectivity control and fast mass transfer for high efficiency separation and moderate capacity.
Numéro de catalogue:
(PRSI91-831)
Fournisseur:
ProSci Inc.
Description:
CXCL16 is a single-pass type I membrane protein, which consists of 246 amino acids, CXCL16 induces a strong chemotatic response and calcium mobilization. CXCL16 acts as a scavenger receptor on macrophages, which specially binds to oxidized low density lipoprotein. CXCL16 may involves in pathophysiology such as atherogenesis. Soluble CXCL16 may play an important role in liver metastases through the induction of epithelial-mesenchymal transition.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-11399R-CY7)
Fournisseur:
Bioss
Description:
Synaptotagmins are a large family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Synaptotagmin XI, also known as SYT11 (Synaptotagmin-11), is a 431 amino acid protein that localizes to the membrane and is expressed ubiquitously with highest expression in brain and lung. Like other Synaptotagmin proteins, Synaptotagmin XI is involved in the calcium-dependent exocytosis of secretory vesicles and is thought to act as a calcium sensor during vesicular trafficking. Synaptotagmin XI contains two C2 domains through which it can bind either three calcium ions or the zinc-finger protein Parkin (a juvenile Parkinson’s disease gene product), the latter of which causes the polyubiquitination and subsequent degradation of Synaptotagmin XI by the proteasome complex. Defects in the gene encoding Synaptotagmin XI are implicated in a number of neurological disorders, including schizophrenia and Parkinson’s disease.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7689R)
Fournisseur:
Bioss
Description:
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open. Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.
UOM:
1 * 100 µl
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