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Solid+Phase+Extraction
Numéro de catalogue:
(BOSSBS-13515R)
Fournisseur:
Bioss
Description:
Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
UOM:
1 * 100 µl
Numéro de catalogue:
(BTIUBNUM0715-50)
Fournisseur:
Biotium
Description:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
UOM:
1 * 50 µl
Fournisseur:
Biotium
Description:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Numéro de catalogue:
(BTIUBNUM0714-50)
Fournisseur:
Biotium
Description:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
UOM:
1 * 50 µl
Fournisseur:
MACHEREY-NAGEL
Description:
These columns contain a silica-based protein phase for HPLC enantiomer separation. The base material is NUCLEOSIL® silica, the chiral selector bovine serum albumin (BSA).
Numéro de catalogue:
(ENZOBMLEA1100005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
AMPA receptor ligand
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI92-072)
Fournisseur:
ProSci Inc.
Description:
Serum Amyloid A-4 Protein (SAA4) is a member of the SAA family. SAA proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA4 is constitutively expressed only in humans and mice. Its physiological function is unknown. SAA4 functions as a major acute phase reactant. SAA4 mRNA and protein occurrence in macrophage derived foam cells of coronary and carotid arteries implied a specific role of human SAA4 during inflammation including atherosclerosis.
UOM:
1 * 50 µG
Fournisseur:
CHIRAL TECHNOLOGIES
Description:
These protein-based columns are suitable for separation of basic compounds. These columns function entirely in the reversed phase chromatographic mode, using buffers with low organic modifier content and at moderate pH values.
Numéro de catalogue:
(PRSI55-622)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Fournisseur:
Restek
Description:
These fused silica columns have midpolarity Crossbond® phase manufactured for column to column reproducibility suited for validated methods.
Fournisseur:
Restek
Description:
These application-specific, midpolarity phase, Crossbond 35% diphenyl/65% dimethyl polysiloxane, columns, are ideal for amines and other basic compounds, including alkylamines, diamines, triamines, ethanolamines, and nitrogen-containing heterocyclics.
Numéro de catalogue:
(PRSI79-556)
Fournisseur:
ProSci Inc.
Description:
The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation
UOM:
1 * 1 EA
Fournisseur:
MOTIC
Description:
CCIS® Plan achromatic Phase objective UC PL Ph 10×/0,25 (WD=17,4 mm), Ph1, Ph1 10x/0,25, Distance de travail: 17,4 mm
Fournisseur:
Thermo Fisher Scientific
Description:
Hypercarb porous graphitic carbon (PGC, Hypercarb) is a unique stationary phase composed of flat sheets of hexagonally arranged carbon atoms with a satisfied valence, as in a very large polynuclear aromatic molecule, it provides extended separation capabilities, enhanced retention of polar compounds and separtion of structurally related analytes with stability at extreme pH and high temperature.
Numéro de catalogue:
(MANA90762)
Fournisseur:
MACHEREY-NAGEL
Description:
This test paper allows the easy detection of arsine (AsH₃) in the gas phase. Arsenic in solutions has to be converted into AsH₃ with Zn/acid and purged from the solution. The Arsine is detected directly at the boundary layer between water and air.
UOM:
1 * 200 ST
Numéro de catalogue:
(ENZOBMLNS1450050)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Serotonin receptor ligand
UOM:
1 * 50 mg
New Product
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