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acids+and+salts+high+purity
Numéro de catalogue:
(PRSI56-577)
Fournisseur:
ProSci Inc.
Description:
NIACR1 acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI96-323)
Fournisseur:
ProSci Inc.
Description:
Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
UOM:
1 * 1 EA
Numéro de catalogue:
(TCIAP0344-1G)
Fournisseur:
TCI
Description:
o-Cresolphthalein complexone tetrasodium salt
UOM:
1 * 1 g
Fournisseur:
Apollo Scientific
Description:
4-Aminophenyl β-D-glucuronide, sodium salt
Numéro de catalogue:
(341088-1G)
Fournisseur:
SIGMA-ALDRICH MICROSCOPY
Description:
1,9-Dimethyl-Methylene Blue zinc chloride double salt has been used for the quantification of sulfated glycosaminoglycans.
UOM:
1 * 1 g
Numéro de catalogue:
(STMC100-0649)
Fournisseur:
STEMCELL Technologies
Description:
The SARS-CoV-2 (ORF3a) Peptide pool is a lyophilised mixture of 66 peptides from open reading frame 3a (ORF3a) protein of SARS-CoV-2. ORF3a is found in both SARS-CoV and SARS-CoV-2 and the two proteins share high sequence similarity. SARS-CoV ORF3a has been shown to cause apoptosis of infected cells and form potassium-sensitive ion channels, modulating the release of viruses. Additionally, it induces ligand-independent downregulation of Type 1 interferon receptor. The sequence similarity between the two proteins suggests it may play a similar role in SARS-CoV-2. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 275 on SARS-CoV-2 ORF3a.
UOM:
1 * 1 Kit
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
Apollo Scientific
Description:
Stable alternative to disodium salt.
Fournisseur:
TCI
Description:
N,N-Diethylglycinesodium salt ≥97.0% (par analyse titrimétrique)
Numéro de catalogue:
(L10364.06)
Fournisseur:
Thermo Scientific
Description:
Chlorophenol red sodium salt
UOM:
1 * 5 g
Fournisseur:
MP Biomedicals
Description:
Gelatin is a heterogeneous mixture of water-soluble proteins of high average molecular weights, present in collagen. The proteins are extracted by boiling skin, tendons, ligaments, bones, etc. in water. Type A gelatin is derived from acid hydrolysed tissue. The charge on a gelatin molecule and its isoelectric point are primarily due to the carboxyl amino and guanidino groups on the side chains. Type A gelatin has 78 to 80 millimoles of free carboxyl groups per 100 g of protein and a pI of 7,0 to 9,0.
Fournisseur:
Cytiva
Description:
XK empty columns are designed for liquid chromatography at low to medium pressure. The user friendly design ensures trouble-free operation with fittings for direct connection to high performance liquid chromatography systems. They are compatible with aqueous solutions and most organic solvents used in liquid chromatography of macromolecules. They are not resistant to acetone, ktones, chlorinated hydrocarbons, aliphatic esters and phenol. Should be avoided: >10% NaOH, >10% HCl, >5% acetic acid and strong mineral acids.
Fournisseur:
Thermo Scientific
Description:
Pravastatin sodium salt hydrate
Numéro de catalogue:
(PRSI6987)
Fournisseur:
ProSci Inc.
Description:
TOX Antibody: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
UOM:
1 * 1 EA
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