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acids+and+salts+high+purity
Numéro de catalogue:
(PRSI33-455)
Fournisseur:
ProSci Inc.
Description:
It recognises a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This mAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyses the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesised as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(40021.)
Fournisseur:
Biotium
Description:
5-Aminoallyl-UTP can be enzymatically incorporated into RNA for subsequent labeling with an amine-reactive fluorescent dye, biotin, or other hapten.
UOM:
1 * 100 µl
Fournisseur:
Thermo Scientific
Description:
1-(3-sulphopropyl)pyridinium hydroxide inner salt 99%
Numéro de catalogue:
(116577192.)
Fournisseur:
MP Biomedicals
Description:
MagBeads Fast Circulating DNA Kit is intended for purification of high-quality circulating DNA (cfDNA) from cell-free body fluids (such as plasma, serum). The purified DNA is suitable for direct use in downstream applications such as PCR, real-time PCR, Biochip analysis and NGS.
UOM:
1 * 1 EA
Numéro de catalogue:
(ENZOALX307037M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
D-myo-Inositol-1,3,4,5,6-pentakisphosphate pentapotassium salt ≥98% (par HPLC)
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI4979)
Fournisseur:
ProSci Inc.
Description:
RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI32-114)
Fournisseur:
ProSci Inc.
Description:
AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases
UOM:
1 * 100 µl
Fournisseur:
TCI
Description:
1-(3-sulphopropyl)pyridinium hydroxide inner salt ≥98.0% (par HPLC, azote total)
Numéro de catalogue:
(GENSD00018)
Fournisseur:
Genscript
Description:
The AmMag Quatro is an automated solution for purification of large-scale, high quality, transfection-grade plasmids from <i>Escherichia coli</i> cultures.
UOM:
1 * 1 ST
New Product
Fournisseur:
Apollo Scientific
Description:
β-Cyclodextrin sulphobutyl ethers sodium salts (DS~10)
Numéro de catalogue:
(PRSI33-768)
Fournisseur:
ProSci Inc.
Description:
Recognises a 485 amino acid protein (55 kDa monomer/110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI33-516)
Fournisseur:
ProSci Inc.
Description:
Reacts with a protein of ~66 kDa, identified as bovine serum albumin (BSA). It is a high affinity antibody and can be used for detection of traces of BSA. Bovine serum albumin (BSA) is an abundant plasma protein in cows that is important for maintaining osmotic pressure in blood plasma for proper distribution of body fluids between intravascular compartments and body tissues. BSA is a common buffer component for immunoglobulin type assays due to good solubility characteristics for water, Ca2+, Na+, K+, fatty acids, hormones and bilirubin. BSA makes up about half of the protein in plasma and represents the most stable and soluble protein in the plasma. It is a suitable reagent for laboratories developing immunoassays, mostly due to its availability, solubility and the numerous functional groups present for coupling. The BSA component contains several lysines that are capable of reacting with conjugation sites of linkers, making it applicable as a carrier protein for antigenic compounds.
UOM:
1 * 1 EA
New Product
Fournisseur:
Merck
Description:
Media is granulated.
Numéro de catalogue:
(APOSBISN0055-5MG)
Fournisseur:
Apollo Scientific
Description:
JC-1 is a cyanine dye that has been used to determine mitochondrial transmembrane potential.
UOM:
1 * 5 mg
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