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Protéines et Peptides
Numéro de catalogue:
(PRSI91-690)
Fournisseur:
ProSci Inc.
Description:
Calmegin (CLGN) is a member of the calreticulin family. Calmegin is a testis-specific endoplasmic reticulum chaperone protein. Calmegin binds calcium ions and interacts with PDILT. Calmegin may play a role in spermatogeneisis and infertility.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-688)
Fournisseur:
ProSci Inc.
Description:
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY can be cleaved into Neuropeptide Y and C-flanking peptide of NPY chain, which regulates energy usage, and it is involved in learning, memory processing, and epilepsy. NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. In addition, NPY increases the proportion of energy stored as fat and blocks nociceptive signals to the brain.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-693)
Fournisseur:
ProSci Inc.
Description:
Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 enhances DNA synthesis and may have a role in cell proliferation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-699)
Fournisseur:
ProSci Inc.
Description:
Interleukin-22 Receptor Subunit alpha-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
UOM:
1 * 50 µG
Fournisseur:
SEQENS
Description:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Numéro de catalogue:
(PRSI4835P)
Fournisseur:
ProSci Inc.
Description:
Rkhd1 peptide is used for blocking the activity of Rkhd1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-056)
Fournisseur:
ProSci Inc.
Description:
Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-554)
Fournisseur:
ProSci Inc.
Description:
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40 L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controllling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40 L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-551)
Fournisseur:
ProSci Inc.
Description:
Lymphocyte-activation gene 3 (LAG3), also known as CD223, is a type I transmembrane protein with four extracellular Ig-like domains, designated D1 to D4 and belongs to the immunoglobulin superfamily. The gene for LAG3 lies adjacent to the gene for CD4 on human chromosome 12p13.32 and shares approximately 20% identical to the CD4 gene. LAG3 is expressed on activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. LAG3 binds with high affinity to MHC class II molecules, and it interferes competitively with the binding of CD4 to MHC class II and thereby blocks the transduction of stimulatory signals mediated by this interaction. LAG3 negatively regulates cellular proliferation, activation, and homeostasis of T cells, and plays an important role in Treg suppressive function. LAG3 is the target of various drug development programs to develop new treatments for cancer and autoimmune disorders. The soluble form, sLAG-3, is being developed as a cancer drug.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-371)
Fournisseur:
ProSci Inc.
Description:
Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signalling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A promotes phosphorylation of TIMD2, inhibits angiogenesis, and promotes axon growth cone collapse, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5877P)
Fournisseur:
ProSci Inc.
Description:
SESTD1 peptide is used for blocking the activity of SESTD1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5883P)
Fournisseur:
ProSci Inc.
Description:
WDR92 peptide is used for blocking the activity of WDR92 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4393P)
Fournisseur:
ProSci Inc.
Description:
Grik4 peptide is used for blocking the activity of Grik4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4501P)
Fournisseur:
ProSci Inc.
Description:
BRAL1 peptide is used for blocking the activity of Bral1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3775P)
Fournisseur:
ProSci Inc.
Description:
TNFRSF14 peptide is used for blocking activity of TNFRSF14 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-045)
Fournisseur:
ProSci Inc.
Description:
Human recombinant CD803 (from HEK293 cells)
UOM:
1 * 1 EA
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