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Protéines et Peptides
Numéro de catalogue:
(PRSI6213P)
Fournisseur:
ProSci Inc.
Description:
Bcl9L peptide is used for blocking the activity of Bcl9L antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6215P)
Fournisseur:
ProSci Inc.
Description:
CTTNBL1 peptide is used for blocking the activity of CTNNBL1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-403)
Fournisseur:
ProSci Inc.
Description:
Human CD83 is a 40-50 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-822)
Fournisseur:
ProSci Inc.
Description:
Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-260)
Fournisseur:
ProSci Inc.
Description:
Human Zinc Finger MYND Domain-Containing Protein 19 (ZMYND19) is a protein that contains 1 MYND-Type Zinc Finger. ZMYND19 can be expressed by the brain, testis, placenta, heart, liver, skeletal muscle, kidney, and stomach. ZMYND19 interacts with GPR24/MCH-R1. It binds to the C terminus of Melanin-Concentrating Hormone Receptor-1 and the N Termini of alpha-Tubulin. ZMYND19 may be involved as a regulatory molecule in GPR24/MCH-R1 signaling.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2059P)
Fournisseur:
ProSci Inc.
Description:
DNase II peptide is used for blocking the antibody. activity of DNase II antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6293P)
Fournisseur:
ProSci Inc.
Description:
PRR5L peptide is used for blocking the activity of PRR5L antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-560)
Fournisseur:
ProSci Inc.
Description:
Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. In the glucagon antagonist, His-53 and Phe-58 are missing. This antagonist has been successfully utilized to reduce glucose concentration in vivo.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-120)
Fournisseur:
ProSci Inc.
Description:
Gamma-Synuclein (SNCG) is a member of the Synuclein protein family. Gamma-Synuclein is mostly expressed in the peripheral nervous system and retina. Gamma-Synuclein plays a role in neurofilament network integrity and may be involved in modulating axonal architecture during development and in the adult. In addition, it may also function in modulating the keratin network in skin. SNCG expression in breast tumours has been as a marker for tumour progression. SNCG is also believed to be involved in the pathogenesis of neurodegenerative diseases.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3455P)
Fournisseur:
ProSci Inc.
Description:
Caspase-5 peptide is used for blocking the activity of Caspase-5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-239)
Fournisseur:
ProSci Inc.
Description:
Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported.
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI92-251)
Fournisseur:
ProSci Inc.
Description:
Zinc finger and BTB domain-containing protein 9 is a protein-coding gene. ZBTB9 is a 473 amino acids protein that Contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. Diseases associated with ZBTB9 include systemic lupus erythematosus, and lupus erythematosus. Zinc finger and BTB domain-containing protein 9 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-250)
Fournisseur:
ProSci Inc.
Description:
Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesised without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-255)
Fournisseur:
ProSci Inc.
Description:
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a heparin binding domain II, which co-locates the cell and the virus vector on NovoNectin. This process enhances the density of both cells and vectors, and facilitates the gene transduction in the result.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-294)
Fournisseur:
ProSci Inc.
Description:
Fatty acid-binding protein 6 (FABP6), is also known as Intestinal bile acid-binding protein (I-BABP), Ileal lipid-binding protein (ILBP), Intestinal 15 kDa protein (I-15P), Gastrotropin (GT). FABP6 is a cytoplasm protein which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Ileal protein FABP6 stimulates gastric acid and pepsinogen secretion. FABP6 seems to be able to bind to bile salts and bilirubins. Isoform 2 of FABP6 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-573)
Fournisseur:
ProSci Inc.
Description:
CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
UOM:
1 * 1 EA
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