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ENZO LIFE SCIENCES


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Numéro de catalogue: (ENZOALX550408M050)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Key intermediate in the breakdown pathway of tryptophan.
UOM:  1 * 50 mg
New Product

Fournisseur:  ENZO LIFE SCIENCES
Description:   Produced in <i>E. coli</i>.
UOM:  1 * 50 µG
New Product
Numéro de catalogue: (ENZOBMLUW98000100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Produced in <i>E. coli</i> and biochemically synthesized in vitro.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOALX270296M001)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Inhibitor of cyclin-dependent kinases (CDKs), with selectivity for CDK1/cyclin B (IC50=55 nm), CDK2/cyclin A (IC50=35 nm), CDK2/cyclin E (IC50=150 nm), CDK4/cyclin D1 (IC50=300 nm), CDK5/p35 (IC50=65 nm) and GSK-3β (IC50=280 nm).
UOM:  1 * 1 mg
New Product
Fournisseur:  ENZO LIFE SCIENCES
Description:   Inhibitor of caspase-3 and -7
New Product
Fournisseur:  ENZO LIFE SCIENCES
Description:   Substrate for caspase-1 and -5
New Product
Fournisseur:  ENZO LIFE SCIENCES
Description:   Soluble, stable and more potent Ang-1 variant.
New Product
Numéro de catalogue: (ENZOALX201283C002)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Produced in SF21 cells. Fused to a His-tag.
UOM:  1 * 2 µG
New Product

Fournisseur:  ENZO LIFE SCIENCES
Description:   Produced in SF21 cells. Human PARP-1 (aa 656-1014) is fused to a His-tag.
UOM:  1 * 20 µG
New Product
Numéro de catalogue: (ENZOALX201242L001)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Produced in E. coli.
UOM:  1 * 1 mL
New Product
Numéro de catalogue: (ENZOALX201124C010)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Produced in CHO cells. Human full-length PTX3.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOBPDABS033101)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Glucagon-like peptide 1 (7-36) amide (GLP-1 (7-36) amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
UOM:  1 * 1 mg
New Product
Numéro de catalogue: (ENZOADIKAPGP125E)

Fournisseur:  ENZO LIFE SCIENCES
Description:   Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ENZOADIKAPTK140E)

Fournisseur:  ENZO LIFE SCIENCES
Description:   SHPS-1 is a member of the gene family called the signal regulatory proteins of which there are at least fifteen members. SHPS-1 is a substrate of many activated tyrosine kinases such as Insulin receptor and EGFR, amongst others. SHPS-1 has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
UOM:  1 * 1 EA
New Product
Fournisseur:  ENZO LIFE SCIENCES
Description:   Cyclic GMP-dependent protein kinases (PKGs or cGKs) are classified into two types, PKGI and PKGII. Studies have shown that PKGs are highly homologous to PKAs; phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility, and platelet aggregation.
New Product
Fournisseur:  ENZO LIFE SCIENCES
Description:   The Akt (PKB) family of protein kinases are serine/threonine kinases, with three mammalian family members identified (Akt1, Akt2, Akt3). Akt is a well-characterized member of PI3 kinase-mediated signaling pathways, regulating cell growth, apoptosis, glycogen synthesis, and other cellular responses through its phosphorylation of downstream substrates. Akt activation is triggered by binding of phospholipid and phosphorylation at two key residues: Thr308 by PDK1, and Ser473 by PDK2, now identified as mTOR. Deregulation of Akt signaling has been associated with cancer, diabetes, and schizophrenia. Akt1 is the cellular homologue of the murine thymoma retroviral oncogene v-akt, and its role in anti-apoptotic and pro-mitotic pathways have made Akt a molecular target for anti-cancer therapeutic intervention. Akt activation inhibits apoptosis by phosphorylating the Bcl-2 related protein Bad, and increases p53 degradation by phosphorylating mdm2. Mitotic substrates of Akt include GSK-3β, p21CIP1, and p27KIP1, cell cycle inhibitors negatively regulated by Akt phosphorylation. Akt has been shown to mediate angiogenesis through regulation of thrombospondins, which may cooperate with pro-mitotic and anti-apoptotic functions of Akt to promote tumorigenesis.
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