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ProSci Inc.
Numéro de catalogue:
(PRSI79-399)
Fournisseur:
ProSci Inc.
Description:
Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI49-331)
Fournisseur:
ProSci Inc.
Description:
Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-401)
Fournisseur:
ProSci Inc.
Description:
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5727P)
Fournisseur:
ProSci Inc.
Description:
APC5 peptide is used for blocking the activity of APC5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5725P)
Fournisseur:
ProSci Inc.
Description:
APC4 peptide is used for blocking the activity of APC4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5735P)
Fournisseur:
ProSci Inc.
Description:
APC10 peptide is used for blocking the activity of APC10 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5437)
Fournisseur:
ProSci Inc.
Description:
GAS Antibody: Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5729P)
Fournisseur:
ProSci Inc.
Description:
APC6 peptide is used for blocking the activity of APC6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5131)
Fournisseur:
ProSci Inc.
Description:
Anti-FGF10 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-306)
Fournisseur:
ProSci Inc.
Description:
Anti-PNPLA2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-454)
Fournisseur:
ProSci Inc.
Description:
Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-895)
Fournisseur:
ProSci Inc.
Description:
Anti-MAOA Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6517)
Fournisseur:
ProSci Inc.
Description:
DRGX Antibody: DRGX, also known as DRG11 or PRRXL1, is a paired homeodomain transcription factor, and was initially cloned from a differential hybridization screen aimed at identifying dorsal root ganglia (DRG)-specific genes. DRGX is a key regulator of the differentiation of the spinal cord neuronal circuit dedicated to the processing of nociceptive information. DRGX is also important for the formation of the whisker-related somatosensory maps in the principal sensory nucleus of the trigeminal nerve, thalamus and somatosensory cortex.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6509)
Fournisseur:
ProSci Inc.
Description:
FCHSD1 Antibody: The FCH and double SH3 domains protein 1 (FCHSD1, also known as NWK2) and the related protein FCHSD2 were initially identified in silico as distantly related proteins to FNBP1 and FNBP2. Both share the common domain structure consisting of FCH, FBH, two SH3 and C-terminal proline-rich domains. While little is known of the function of FCHSD1, the related protein NWK is an adaptor protein that is thought to regulate Rho activity downstream of Robo receptors, suggesting that FCHSD1 may be involved in synaptic morphology by regulating actin dynamics in presynaptic terminals.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-326)
Fournisseur:
ProSci Inc.
Description:
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-322)
Fournisseur:
ProSci Inc.
Description:
SULT6B1 belongs to the sulfotransferase 1 family. SULT6B1 may catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters.
UOM:
1 * 50 µG
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