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ProSci Inc.
Numéro de catalogue:
(PRSI29-450)
Fournisseur:
ProSci Inc.
Description:
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-433)
Fournisseur:
ProSci Inc.
Description:
The function remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-719)
Fournisseur:
ProSci Inc.
Description:
Lysozyme G-Like Protein 2 (LYG2) is a secreted protein that belongs to the glycosyl hydrolase 23 family. LYG2 contains one SLT domain, one protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryotic lysozymes (GEWL). SLT domain catalyzes the cleavage of the beta -1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyglucosamine (GlcNAc). LYG2 has hydrolase activity which acting on glycosyl bonds, and possess lysozyme activity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-841)
Fournisseur:
ProSci Inc.
Description:
Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXG-6129)
Fournisseur:
ProSci Inc.
Description:
Anti-ABCG1 Chicken Polyclonal Antibody
UOM:
1 * 500 µG
Numéro de catalogue:
(PRSIXG-6111)
Fournisseur:
ProSci Inc.
Description:
Anti-SERPINA1 Chicken Polyclonal Antibody
UOM:
1 * 500 µG
Numéro de catalogue:
(PRSI79-592)
Fournisseur:
ProSci Inc.
Description:
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-588)
Fournisseur:
ProSci Inc.
Description:
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXG-6133)
Fournisseur:
ProSci Inc.
Description:
Anti-GHRL Chicken Polyclonal Antibody
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSIXG-6130)
Fournisseur:
ProSci Inc.
Description:
Anti-APP Chicken Polyclonal Antibody
UOM:
1 * 500 µG
Numéro de catalogue:
(PRSIXG-6118)
Fournisseur:
ProSci Inc.
Description:
Anti-DNAJC28 Chicken Polyclonal Antibody
UOM:
1 * 500 µG
Numéro de catalogue:
(PRSI32-167)
Fournisseur:
ProSci Inc.
Description:
GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI32-174)
Fournisseur:
ProSci Inc.
Description:
IGF1R(insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI26-121)
Fournisseur:
ProSci Inc.
Description:
TSR1 belongs to the BMS1/TSR1 family and TSR1 subfamily. TSR1 is required during maturation of the 40S ribosomal subunit in the nucleolus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-126)
Fournisseur:
ProSci Inc.
Description:
The function of the C2orf47 protein remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3001P)
Fournisseur:
ProSci Inc.
Description:
Lano peptide is used for blocking the activity of MTBP antibody.
UOM:
1 * 50 µG
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