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ProSci Inc.
Numéro de catalogue:
(PRSI28-791)
Fournisseur:
ProSci Inc.
Description:
Extracellular HMGB1 is an activator of human tumor cell migration operating in concert with EGF. HMGB1 encodes a protein that is potentially involved in the regulation of lipogenic and cholesterogenic gene transcription.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-081)
Fournisseur:
ProSci Inc.
Description:
HNF4 was first identified as a DNA binding activity in rat liver nuclear extracts and then was found to be an orphan member of the nuclear receptor superfamily. Binding sites for this factor were identified in many tissue-specifically expressed genes, and the protein was found to be essential for early embryonic development in the mouse
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-339)
Fournisseur:
ProSci Inc.
Description:
Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of the ILF2 gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-338)
Fournisseur:
ProSci Inc.
Description:
The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-346)
Fournisseur:
ProSci Inc.
Description:
The DLX6 gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. This family is comprised of at least 6 different members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-347)
Fournisseur:
ProSci Inc.
Description:
The human HMG2a gene is transcribed mainly in the placenta. HMG2a encodes a protein which is part of the high mobility group (HMG) family. Members of this family are ubiquitously expressed and facilitate the formation of nucleoprotein complexes where the DNA is sharply bent.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-342)
Fournisseur:
ProSci Inc.
Description:
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-285)
Fournisseur:
ProSci Inc.
Description:
Anti-DIAPH1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-521)
Fournisseur:
ProSci Inc.
Description:
SSX5 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. The gene encoding SSX5 appears not to be involved in this type of chromosome translocation. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-085)
Fournisseur:
ProSci Inc.
Description:
The function of the C21orf59 protein remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-089)
Fournisseur:
ProSci Inc.
Description:
The function of the C21orf13 protein remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4929P)
Fournisseur:
ProSci Inc.
Description:
JPH2 peptide is used for blocking the activity of JPH2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4923P)
Fournisseur:
ProSci Inc.
Description:
JPH4 peptide is used for blocking the activity of JPH4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXW-7816)
Fournisseur:
ProSci Inc.
Description:
FUNCTION: The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. SUBUNIT: Interacts with GRIP1 (By similarity). Interacts with PPFIA1, PPFIA2 and PPFIA3.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-887)
Fournisseur:
ProSci Inc.
Description:
Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-693)
Fournisseur:
ProSci Inc.
Description:
ZBTB38 physically associates with CtBP via a conserved CtBP binding motif, PLDLR. When heterologously targeted to DNA, it represses transcription via two independent repression domains, an N-terminal BTB domain and a PLDLR motif-containing RD2 region, in a histone deacetylase-independent and -dependent manner, respectively
UOM:
1 * 50 µG
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