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ProSci Inc.
Numéro de catalogue:
(PRSI26-405)
Fournisseur:
ProSci Inc.
Description:
MDM1 is a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles and is amplified in the mouse transformed 3T3 cell line, and the protein is able to bind to p53. This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles and is amplified in the mouse transformed 3T3 cell line, and the protein is able to bind to p53. In mouse several transcripts have been described for this gene which result from alternative polyadenylation, splicing and exon usage.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-518)
Fournisseur:
ProSci Inc.
Description:
Anti-Hepatitis C Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-309)
Fournisseur:
ProSci Inc.
Description:
S100A6, also known as Protein S100-A6, Calcyclin, Growth factor-inducible protein 2A9, MLN 4, Prolactin receptor-associated protein, PRA, S100 calcium-binding protein A6 and CACY, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are a family of low molecular weight protein found in vertebrates and localised in the cytoplasm and/or nucleus of a wide range of cells.S100 proteins are involved in a number of fundamental biological processes such as protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, the inflammatory response,cell cycle progression and differentiation, stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. S100A6 may function as calcium sensor and modulator, contributing to cellular calcium signaling.It may function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganisation of the actin cytoskeleton and in cell motility.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-096)
Fournisseur:
ProSci Inc.
Description:
Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD; MIM 114010), which has been mapped to 2p21.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-099)
Fournisseur:
ProSci Inc.
Description:
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-082)
Fournisseur:
ProSci Inc.
Description:
HNF4 was first identified as a DNA binding activity in rat liver nuclear extracts and then was found to be an orphan member of the nuclear receptor superfamily. Binding sites for this factor were identified in many tissue-specifically expressed genes, and the protein was found to be essential for early embryonic development in the mouse
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-799)
Fournisseur:
ProSci Inc.
Description:
Anti-KIF5A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-798)
Fournisseur:
ProSci Inc.
Description:
Anti-KIF4A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-796)
Fournisseur:
ProSci Inc.
Description:
Anti-KCNC3 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-305)
Fournisseur:
ProSci Inc.
Description:
CCND2，also known as G1/S-specific cyclin-D2，is a member of the highly conserved cyclin family. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 is involved in a number of fundamental biological processes such as phosphorylating and inhibiting members of the retinoblastoma (RB) protein family including RB1 and regulating the cell-cycle during G1/S transition. It is also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-740)
Fournisseur:
ProSci Inc.
Description:
Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little elastolytic activity. ELA3A preferentially cleaves proteins after alanine residues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-778)
Fournisseur:
ProSci Inc.
Description:
C4orf33 belongs to the UPF0462 family. The exact function of C4orf33 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-022)
Fournisseur:
ProSci Inc.
Description:
Anti-FEM1A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-028)
Fournisseur:
ProSci Inc.
Description:
Anti-CDKAL1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-018)
Fournisseur:
ProSci Inc.
Description:
Anti-Tankyrase 2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-765)
Fournisseur:
ProSci Inc.
Description:
Septin-9 is a member of the septin family, which contains cytoplasmic cytoskeletal filament-forming proteins that have a conserved GTP-binding domain.Septin-9 is a member of the septin family, which contains cytoplasmic cytoskeletal filament-forming proteins that have a conserved GTP-binding domain (Osaka et al., 1999 [PubMed 10339604]).
UOM:
1 * 50 µG
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