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Numéro de catalogue: (PRSI26-680)

Fournisseur:  ProSci Inc.
Description:   PPM1M belongs to the PP2C family. It contains 1 PP2C-like domain. The exact function of PPM1M is not known.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-755)

Fournisseur:  ProSci Inc.
Description:   UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-757)

Fournisseur:  ProSci Inc.
Description:   PIPOX metabolizes sarcosine, L-pipecolic acid and L-proline.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSIPM-4937)

Fournisseur:  ProSci Inc.
Description:   XBP-1 Monoclonal Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-534)

Fournisseur:  ProSci Inc.
Description:   Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
UOM:  1 * 1 EA

Fournisseur:  ProSci Inc.
Description:   HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-540)

Fournisseur:  ProSci Inc.
Description:   Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-544)

Fournisseur:  ProSci Inc.
Description:   Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-547)

Fournisseur:  ProSci Inc.
Description:   Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-522)

Fournisseur:  ProSci Inc.
Description:   Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI38-231)

Fournisseur:  ProSci Inc.
Description:   BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
UOM:  1 * 500 µG
Numéro de catalogue: (PRSI45-859)

Fournisseur:  ProSci Inc.
Description:   Anti-SCGB2A2 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI45-854)

Fournisseur:  ProSci Inc.
Description:   Anti-MXD3 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI45-853)

Fournisseur:  ProSci Inc.
Description:   Anti-MAD2L1 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI38-229)

Fournisseur:  ProSci Inc.
Description:   Anti-IL17F Rabbit Polyclonal Antibody (Biotin)
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI92-349)

Fournisseur:  ProSci Inc.
Description:   Promotilin is a 115 amino acids protein that belongs to the motilin family. It is a secreted protein that plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
UOM:  1 * 50 µG
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