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ProSci Inc.
Numéro de catalogue:
(PRSI92-546)
Fournisseur:
ProSci Inc.
Description:
Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-990)
Fournisseur:
ProSci Inc.
Description:
MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-997)
Fournisseur:
ProSci Inc.
Description:
BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-998)
Fournisseur:
ProSci Inc.
Description:
CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-004)
Fournisseur:
ProSci Inc.
Description:
CBX6 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-911)
Fournisseur:
ProSci Inc.
Description:
Anti-HP Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-919)
Fournisseur:
ProSci Inc.
Description:
Anti-SLC5A1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-922)
Fournisseur:
ProSci Inc.
Description:
Anti-Pard3b Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-437)
Fournisseur:
ProSci Inc.
Description:
Cytochrome b5 type B (CYB5B) is a membrane of the cytochrome b5 family. It contains 1 cytochrome b5 heme-binding domain. Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. In the mitochondrion of eukaryotes and in aerobic prokaryotes, cytochrome b is a component of respiratory chain complex III also known as the bc1 complex or ubiquinol-cytochrome c reductase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-432)
Fournisseur:
ProSci Inc.
Description:
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signalling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-435)
Fournisseur:
ProSci Inc.
Description:
Hematopoietic lineage cell-specific protein (HCLS1) is a protein that in humans is encoded by the HCLS1 gene. It is expressed only in tissues and cells of hematopoietic origin. It is substrate of the antigen receptor-coupled tyrosine kinase and plays a role in antigen receptor signalling for both clonal expansion and deletion in lymphoid cells. It may also be involved in the regulation of gene expression.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-472)
Fournisseur:
ProSci Inc.
Description:
Anti-Parainfluenza Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI35-467)
Fournisseur:
ProSci Inc.
Description:
Anti-Influenza Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-510)
Fournisseur:
ProSci Inc.
Description:
Retinal Homeobox Protein Rx (RAX) is a member of homeobox family of transcription factors. Mutations mouse and fish RAX lead to defects in retinal development and result in animal models of anophthalmia.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-516)
Fournisseur:
ProSci Inc.
Description:
D-site-binding protein (DBP) is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-520)
Fournisseur:
ProSci Inc.
Description:
DLX3 is a member of the Dlx gene family which contains a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less homeo box (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.
UOM:
1 * 50 µG
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