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ProSci Inc.
Numéro de catalogue:
(PRSI28-004)
Fournisseur:
ProSci Inc.
Description:
NPM3 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-003)
Fournisseur:
ProSci Inc.
Description:
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals which contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-410)
Fournisseur:
ProSci Inc.
Description:
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-416)
Fournisseur:
ProSci Inc.
Description:
Results suggest that RZF is a shuttling regulatory protein expressed in photoreceptors of the human retina that may be involved in mRNA or protein regulation of photoreceptor-specific genes and therefore have role in retinal disease mechanisms.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-427)
Fournisseur:
ProSci Inc.
Description:
GFI1 may be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. GFI1 may be involved in tumor progression. Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) and dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA)
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-424)
Fournisseur:
ProSci Inc.
Description:
Altered expression of GBX2, part of the homeobox-containing human family of DNA-binding transcription factors, is associated with therapy failure and death in patients with multiple types of cancer.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7441P)
Fournisseur:
ProSci Inc.
Description:
13 amino acids near the amino terminus of TFPI.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-368)
Fournisseur:
ProSci Inc.
Description:
Anti-Salmonella Rabbit Polyclonal Antibody (Biotin)
UOM:
1 * 1 mL
Numéro de catalogue:
(PRSI30-726)
Fournisseur:
ProSci Inc.
Description:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. JPH2 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-720)
Fournisseur:
ProSci Inc.
Description:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-737)
Fournisseur:
ProSci Inc.
Description:
PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-724)
Fournisseur:
ProSci Inc.
Description:
ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-649)
Fournisseur:
ProSci Inc.
Description:
Anti-PSMB7 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-174)
Fournisseur:
ProSci Inc.
Description:
CMRF35-like molecule 9 (CLM-9) is also known as CD300 antigen-like family member G (CD300LG or CD300g), Nepmucin, Triggering receptor expressed on myeloid cells 4 (TREM-4), which belongs to the CD300 family. CD300LG contains one Ig-like V-type (immunoglobulin-like) domain. CD300LG is highly expressed in heart, skeletal muscle and placenta. CD300LG is a receptor which may mediate L-selectin-dependent lymphocyte rollings. CD300LG binds SELL in a calcium dependent manner and also binds lymphocyte.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-354)
Fournisseur:
ProSci Inc.
Description:
Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilises intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI38-230)
Fournisseur:
ProSci Inc.
Description:
Anti-IL2RA Mouse Monoclonal Antibody
UOM:
1 * 500 µG
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