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Fournisseur:  ProSci Inc.
Description:   CD45, also referred to as CD45R and PTPRC (Protein tyrosine phosphatase receptor type C), has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Along with other members of the PTP family, it regulates a number of cellular processes including cell differentiation, growth and mitotic cycle, and is an essential regulator of B- and T-cell antigen receptor-mediated activation. <p>Multiple isoforms of CD45 are distributed throughout the immune system and arise due to alternative splicing of exons located in the N-terminus. CD45RA contains the A exon and is a naive T-cell marker which may help prevent autoimmune disease. CD45RB contains B and stains most leukemias and lymphomas. CD45RC contains C and stains thymocytes, monocytes and dendritic cells. CD45RO doesn't contain A, B or C and is a marker of activated T-cells that can be used to classify and diagnose and classify lymphomas. This antibody will bind to all CD45 isoforms. The variation in these isoforms is localized to the extracellular domain, with the intracellular domain being conserved. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   Ten to forty percent of the patients with acquired immunodeficiency syndrome (AIDS) develop cytomegalovirus (CMV) infections. In some patients with AIDS, cytomegalovirus is detected in the bronchoalveolar lavage fluid (BALF), urine, and other specimens, even when there are no symptoms of cytomegalovirus disease. An indicator of active CMV infection is needed to facilitate the diagnosis of cytomegalovirus disease in patients with AIDS or HIV infection. Cytomegalovirus p65 antigen was detected in the leukocytes of both the peripheral blood and BALF during the early phase of CMV disease.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (PRSI33-276)

Fournisseur:  ProSci Inc.
Description:   CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   This antibody recognises proteins of 80-200 kDa, identified as different members of the CEA (Carcinoembryonic Antigen) family. CEA is synthesised during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. The antibody shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). CEA antibody positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   Cluster of Differentiation 8 is a cell surface receptor expressed either as a heterodimer with the beta chain or as a homodimer. A majority of thymocytes and a subpopulation of mature Tcells and NK cells express CD8a. It binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in Tcell development and activation of mature Tcells. For mature Tcells, CD4 and 8 are mutually exclusive, so antibody to CD8 is generally used in conjunction with antibody to CD4.
UOM:  1 * 1 EA
New Product

Fournisseur:  ProSci Inc.
Description:   CD45, also referred to as CD45R and PTPRC (Protein tyrosine phosphatase receptor type C), has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Along with other members of the PTP family, it regulates a number of cellular processes including cell differentiation, growth and mitotic cycle, and is an essential regulator of B- and T-cell antigen receptor-mediated activation. <p>Multiple isoforms of CD45 are distributed throughout the immune system and arise due to alternative splicing of exons located in the N-terminus. CD45RA contains the A exon and is a naive T-cell marker which may help prevent autoimmune disease. CD45RB contains B and stains most leukemias and lymphomas. CD45RC contains C and stains thymocytes, monocytes and dendritic cells. CD45RO doesn't contain A, B or C and is a marker of activated T-cells that can be used to classify and diagnose and classify lymphomas. Clone 2B11 antibody will bind to all CD45 isoforms. The variation in these isoforms is localized to the extracellular domain, with the intracellular domain being conserved. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (PRSI57-195)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI57-196)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI62-172)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI57-204)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI57-210)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI57-206)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI19-435)

Fournisseur:  ProSci Inc.
Description:   Anti-CRCP Rabbit Polyclonal Antibody
UOM:  1 * 50 µl
New Product
Numéro de catalogue: (PRSI19-439)

Fournisseur:  ProSci Inc.
Description:   Anti-IFT81 Rabbit Polyclonal Antibody
UOM:  1 * 50 µl
New Product
Numéro de catalogue: (PRSI18-213)

Fournisseur:  ProSci Inc.
Description:   Anti-PIP5K1A Rabbit Polyclonal Antibody
UOM:  1 * 50 µl
New Product
Numéro de catalogue: (PRSI18-225)

Fournisseur:  ProSci Inc.
Description:   Anti-PSIP1 Rabbit Polyclonal Antibody
UOM:  1 * 50 µl
New Product
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