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Numéro de catalogue:
(PRSI79-150)
Fournisseur:
ProSci Inc.
Description:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-135)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-153)
Fournisseur:
ProSci Inc.
Description:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7695)
Fournisseur:
ProSci Inc.
Description:
The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology: C type (canonical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPV4, belongs to the V type subfamily and plays a role in systemic osmoregulation. TRPV4 is a calcium channel multi-pass membrane protein activated by various stimuli, including thermal stress, fatty acid metabolites and hypotonicity. TRPV4 is highly expressed in lung and kidney and widely expressed in brain. It plays an important role in regulating neural excitability.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI2237P)
Fournisseur:
ProSci Inc.
Description:
Survivin peptide is used for blocking the activity of Survivin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-084)
Fournisseur:
ProSci Inc.
Description:
Anti-LEPR Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI35-588)
Fournisseur:
ProSci Inc.
Description:
Anti-Papilloma virus Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI35-579)
Fournisseur:
ProSci Inc.
Description:
Anti-SARS Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5797)
Fournisseur:
ProSci Inc.
Description:
ATG9B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-840)
Fournisseur:
ProSci Inc.
Description:
CHFR is an E3 ubiquitin-protein ligase required to transiently arrest cells in early prophase when they are exposed to microtubule poisons. It acts in early prophase before chromosome condensation, when the centrosome moves apart from each other along the periphery of the nucleus. CHFR probably promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress. This suggests that it may be involved in signaling the presence of mitotic stress caused by microtubule poisons.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-837)
Fournisseur:
ProSci Inc.
Description:
MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1105P)
Fournisseur:
ProSci Inc.
Description:
CCR3 peptide is used for blocking the activity of CCR3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6179P)
Fournisseur:
ProSci Inc.
Description:
OGFOD2 peptide is used for blocking the activity of OGFOD2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-913)
Fournisseur:
ProSci Inc.
Description:
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI35-345)
Fournisseur:
ProSci Inc.
Description:
Anti-Pseudomonas Rabbit Polyclonal Antibody
UOM:
1 * 1 mL
Numéro de catalogue:
(PRSI46-575)
Fournisseur:
ProSci Inc.
Description:
Anti-VPS11 Goat Polyclonal Antibody
UOM:
1 * 1 EA
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