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ProSci Inc.
Numéro de catalogue:
(PRSI27-991)
Fournisseur:
ProSci Inc.
Description:
RGS13 encodes a protein which is a member of the regulator of G protein signaling (RGS) family. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI40-601)
Fournisseur:
ProSci Inc.
Description:
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI40-597)
Fournisseur:
ProSci Inc.
Description:
IL-16 was initially identified as a chemotactic cytokine (1), but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases (2). The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4 (3,4). Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation (5) and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders (6). At least two isoforms of IL-16 are known to exist; the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus (7). This recombinant protein fragment is derrived from this longer isoform.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-236)
Fournisseur:
ProSci Inc.
Description:
RBMY1A1 is a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. The gene that encodes RBMY1A1 is Y-linked. RBMY1A1 may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre-mRNA splicing in the testis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-231)
Fournisseur:
ProSci Inc.
Description:
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3077)
Fournisseur:
ProSci Inc.
Description:
PAK4 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK4 was initially identified as a novel effector of Cdc42Hs. Co-expression of PAK4 and Cdc42Hs resulted in induction of filopodia and actin polymerization, showing that it is involved in cytoskeletal reorganization. Other experiments have shown PAK4 to be essential for embryonic viability and proper neuronal development. PAK4 has also been implicated in anchorage-independent growth of tumor cells and is required for activation of several cancer prosurvival pathways.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-572)
Fournisseur:
ProSci Inc.
Description:
FLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXA-1033)
Fournisseur:
ProSci Inc.
Description:
Anti-NLRP3 Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXA-1007)
Fournisseur:
ProSci Inc.
Description:
Anti-CLU Mouse Monoclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-107)
Fournisseur:
ProSci Inc.
Description:
VAX1 is a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. It may play an important role in the development of anterior ventral forebrain and visual system.This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-108)
Fournisseur:
ProSci Inc.
Description:
LOC390874 is a new protein with unknown function.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-715)
Fournisseur:
ProSci Inc.
Description:
The functions of Voltage-gated potassium (Kv) channels include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNAB2 is a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5825P)
Fournisseur:
ProSci Inc.
Description:
ZEB1 peptide is used for blocking the activity of ZEB1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5803P)
Fournisseur:
ProSci Inc.
Description:
USP10 peptide is used for blocking the activity of USP10 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5497)
Fournisseur:
ProSci Inc.
Description:
CLPH Antibody: CLPH (Casein-Like phosphoprotein) is a recently discovered, evolutionarily conserved, testis-specific cytoplasmic protein expressed exclusively in postmeiotic germ cells in rat spermatogenesis. CLPH is a novel casein kinase 2-phosphorylated disordered and calcium-binding protein that displays strong variation in relative expression levels during spermatogenesis. It is frequently associated with the mitochondrial inner membrane during the last steps of spermatid differentiation and is involved in the extremely complex structural rearrangements occurring in haploid germ cells during spermiogenesis.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5511)
Fournisseur:
ProSci Inc.
Description:
CCDC47 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. The CCDC47 gene maps to chromosome 17 at 17q23.3. Little is known about this single-pass membrane protein except that the coiled-coil domain is within the cytosolic domain near the carboxy terminus.
UOM:
1 * 1 EA
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