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Numéro de catalogue: (PRSI5123)

Fournisseur:  ProSci Inc.
Description:   ZBED3 Antibody: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI92-287)

Fournisseur:  ProSci Inc.
Description:   Protachykinin-1(TAC1) is a secreted protein and belongs to the tachykinin family. TAC1 is encoded by the TAC1 gene. This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI96-241)

Fournisseur:  ProSci Inc.
Description:   Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-516)

Fournisseur:  ProSci Inc.
Description:   In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-523)

Fournisseur:  ProSci Inc.
Description:   NSUN6 may have S-adenosyl-L-methionine-dependent methyl-transferase activity (Potential). NSUN6 belongs to the methyltransferase superfamily, RsmB/NOP family. It contains 1 PUA domain.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI27-813)

Fournisseur:  ProSci Inc.
Description:   SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI27-830)

Fournisseur:  ProSci Inc.
Description:   This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI42-964)

Fournisseur:  ProSci Inc.
Description:   Anti-SLC6A3 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI42-962)

Fournisseur:  ProSci Inc.
Description:   Anti-Clu Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI27-239)

Fournisseur:  ProSci Inc.
Description:   The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI42-974)

Fournisseur:  ProSci Inc.
Description:   Anti-ZIC3 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI28-575)

Fournisseur:  ProSci Inc.
Description:   ESX1 is a homeobox gene related to the mouse Esx1 homeobox gene. ESX1 is expressed during all stages of placental development and is localized to sparse areas of trophoblast in terminal villi in association with cytotrophoblastic cells. Proteolytic processing of ESX1 plays a role in concerted regulation of the cell cycle and transcription in human cells.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI6873)

Fournisseur:  ProSci Inc.
Description:   DBX2 Antibody: DBX2 is a member of the developing brain homeobox (DBX) protein family, but while the related protein DBX1 is expressed in various regions of the developing brain, DBX2 shows a more restricted pattern of expression in the brain, and is also expressed in some mesenchymal cells such as limb buds and tooth germs. It is thought that DBX1 and DBX2 promote the development of a subset of interneurons, some of which help mediate left-right coordination of locomotor activity. In Xenopus, DBX2 is involved in primary neurogenesis and early neural plate patterning, and is thought to act as a cross-repressive partner of NKX6-2 in the patterning of the ventral neural tube.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI5545P)

Fournisseur:  ProSci Inc.
Description:   Girdin peptide is used for blocking the activity of Girdin antibody.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI7237P)

Fournisseur:  ProSci Inc.
Description:   15 amino acid peptide near the carboxy terminus of human PIBF1.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI7249P)

Fournisseur:  ProSci Inc.
Description:   16 amino acid peptide near the carboxy terminus of human RRAS2.
UOM:  1 * 50 µG
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