ProSci Inc.
Numéro de catalogue:
(PRSI3377P)
Fournisseur:
ProSci Inc.
Description:
ECSIT peptide is used for blocking the activity of the ECSIT antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI35-156)
Fournisseur:
ProSci Inc.
Description:
Anti-Cytomegalovirus Goat Polyclonal Antibody (Biotin)
UOM:
1 * 1 mL
Numéro de catalogue:
(PRSI25-167)
Fournisseur:
ProSci Inc.
Description:
CTRC is a member of the peptidase S1 family. The protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-169)
Fournisseur:
ProSci Inc.
Description:
KIF13B may be involved in reorganization of the cortical cytoskeleton. KIF13B may be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-180)
Fournisseur:
ProSci Inc.
Description:
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3399P)
Fournisseur:
ProSci Inc.
Description:
IRF3 peptide is used for blocking the activity of IRF3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3401P)
Fournisseur:
ProSci Inc.
Description:
IRF8 peptide is used for blocking the activity of IRF8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-098)
Fournisseur:
ProSci Inc.
Description:
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-096)
Fournisseur:
ProSci Inc.
Description:
The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Mutations in neuronal nicotinic acetylcholine receptor beta 2 subunit have been associated with autosomal dominant nocturnal frontal lobe epilepsies.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-093)
Fournisseur:
ProSci Inc.
Description:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA7 is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from CHRNA7 and a novel FAM7A gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-099)
Fournisseur:
ProSci Inc.
Description:
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-497)
Fournisseur:
ProSci Inc.
Description:
Anti-DRD5 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-483)
Fournisseur:
ProSci Inc.
Description:
Anti-DKC1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI30-286)
Fournisseur:
ProSci Inc.
Description:
SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI47-109)
Fournisseur:
ProSci Inc.
Description:
Anti-TSG101 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-213)
Fournisseur:
ProSci Inc.
Description:
SMN1 localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein.This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. However, mutations in this gene, the telomeric copy, are associated with spinal muscular atrophy; mutations in the centromeric copy do not lead to disease. The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7 which is thought to be an exon splice enhancer. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Two transcript variants are produced by this gene.
UOM:
1 * 50 µG
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