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ProSci Inc.
Numéro de catalogue:
(PRSI90-270)
Fournisseur:
ProSci Inc.
Description:
IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-267)
Fournisseur:
ProSci Inc.
Description:
Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Abnormal expression of Periostin is also linked to angiogenesis and metastasis in epithelial tumours.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-276)
Fournisseur:
ProSci Inc.
Description:
RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-534)
Fournisseur:
ProSci Inc.
Description:
MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-535)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-542)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3595P)
Fournisseur:
ProSci Inc.
Description:
IRAK2 peptide is used for blocking the activity of IRAK2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3583P)
Fournisseur:
ProSci Inc.
Description:
T-cadherin peptide is used for blocking the activity of T-cadherin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3579P)
Fournisseur:
ProSci Inc.
Description:
CTRP7 peptide is used for blocking the activity of the CTRP7 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7649)
Fournisseur:
ProSci Inc.
Description:
The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-983)
Fournisseur:
ProSci Inc.
Description:
PTPLAD2 is a multi-pass membrane protein. It belongs to the PTPLA family. The function of the PTPLAD2 protein remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7651)
Fournisseur:
ProSci Inc.
Description:
SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-022)
Fournisseur:
ProSci Inc.
Description:
DAGLB belongs to the AB hydrolase superfamily.It catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. This protein is required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-020)
Fournisseur:
ProSci Inc.
Description:
In vitro, MAPK15 phosphorylates MBP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-019)
Fournisseur:
ProSci Inc.
Description:
Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-039)
Fournisseur:
ProSci Inc.
Description:
The exact function of MGC26647 remains unknown.
UOM:
1 * 50 µG
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